{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:33:14Z","timestamp":1788931994331,"version":"build-2803163510"},"reference-count":60,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"unspecified","delay-in-days":261,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS Spectr."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1092852925100497_sec1\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Much work has been done on the role of trauma in obsessive\u2013compulsive disorder (OCD), but the relationship between stressful life events (SLEs) and the onset of OCD remains poorly studied. This study aims to summarize the evidence about the association between SLEs and OCD development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1092852925100497_sec2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>For this systematic review, we searched PubMed, Web of Science, Scopus, and PsycINFO databases for studies published from the database\u2019s inception to December 12, 2024. We included studies investigating the prevalence of SLEs among individuals diagnosed with OCD compared to other psychiatric disorders or healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1092852925100497_sec3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seven studies met the inclusion criteria and were incorporated. Two studies found that OCD patients suffered more SLEs than healthy controls in the year before the onset of OCD. Two of the included studies showed a higher occurrence of SLEs across the patients\u2019 lifetime before the onset of OCD. Three studies were comparable and, therefore, meta-analyzable. Together, they revealed that SLEs in the year before the onset of OCD were associated with a small yet positive pooled effect size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1092852925100497_sec4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our review suggests that SLEs may be highly represented among people with OCD both in the year preceding the disorder\u2019s onset and throughout their lifetime.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1092852925100497","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:27:37Z","timestamp":1758277657000},"source":"Crossref","is-referenced-by-count":4,"title":["Stressful life events as precipitants of obsessive\u2013compulsive disorder: a systematic review and 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