{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:08:03Z","timestamp":1789020483648,"version":"build-2803163510"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"unspecified","delay-in-days":218,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS Spectr."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1092852926101151_sec1\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Impairments in spatial working memory (SWM) have been observed in several disparate psychiatric conditions. The present study investigated how SWM varied across a range of psychiatric disorders in a large sample of young adults using the SWM test from the Cambridge Neuropsychological Test Automated Battery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1092852926101151_sec2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A sample of 575 participants aged 18\u201329\u00a0years was enrolled from the general community and evaluated for psychiatric disorders using several screening evaluations. Performance on the SWM test was assessed, with outcome measures of strategy and total errors. Using\n                      <jats:italic>Z<\/jats:italic>\n                      -scores and Cohen\u2019s\n                      <jats:italic>d<\/jats:italic>\n                      effect sizes, SWM was compared between each psychiatric disorder and healthy controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1092852926101151_sec3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The majority of psychiatric diagnoses examined demonstrated SWM deficits in both strategy and total errors. Large effect sizes in strategy were observed for bulimia, post-traumatic stress disorder, major depressive disorder, social phobia, and agoraphobia. Large effect sizes in total errors were observed for agoraphobia, major depressive disorder, social phobia, intermittent explosive disorder, obsessive-compulsive disorder, bulimia, post-traumatic stress disorder, and gambling disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1092852926101151_sec4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings suggest that SWM impairment is a transdiagnostic element of psychiatric illness rather than serving as a specific feature of any one diagnosis. Future directions include the exploration of how SWM deficits may be utilized in prognostic and therapeutic interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1092852926101151","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:11:39Z","timestamp":1786083099000},"source":"Crossref","is-referenced-by-count":0,"title":["Spatial working memory across psychiatric disorders in young adults"],"prefix":"10.1017","volume":"31","author":[{"given":"Kenneth","family":"Wang","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/024mw5h28","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Chicago Division of the Biological Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7784-7021","authenticated-orcid":false,"given":"Jon E.","family":"Grant","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/024mw5h28","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Chicago Division of the Biological Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,8,7]]},"container-title":["CNS Spectrums"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1092852926101151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:03:32Z","timestamp":1789020212000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1092852926101151\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026]]}},"alternative-id":["S1092852926101151"],"URL":"https:\/\/doi.org\/10.1017\/s1092852926101151","relation":{},"ISSN":["1092-8529","2165-6509"],"issn-type":[{"value":"1092-8529","type":"print"},{"value":"2165-6509","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e32"}}