{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T23:40:17Z","timestamp":1656891617850},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"unspecified","delay-in-days":16740,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta genet. med. gemellol."],"published-print":{"date-parts":[[1968,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Studies on the glucose-6-phosphate dehydrogenase activity of erythrocytes from 416 males and 820 females are reported. The total number of deficient males (intermediate + complete) varied from 3.9% among the whites (102 persons) to 15.1% among Dark Mulattoes (99 individuals); the incidence in the Negroid sample in general (316 persons) was 12.4%. The data obtained among the women were utilized to study problems of penetrance of the G-6-PDD genes. Results obtained in both sexes were employed to verify, unsuccessfully, possible selection differentials through age analysis and the comparison of the gene incidences of people affected with minor ailments and controls. Problems of gene flow analysis in populations like this one in which the \u201cNegro\u201d and \u201cWhite\u201d forms of the deficiency are present were stressed.<\/jats:p>","DOI":"10.1017\/s1120962300012464","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T09:50:23Z","timestamp":1469613023000},"page":"595-606","source":"Crossref","is-referenced-by-count":2,"title":["G-6-PD Deficiency Gene Dynamics in a Brazilian Population"],"prefix":"10.1017","volume":"17","author":[{"given":"F.","family":"Lewgoy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. M.","family":"Salzano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,8,1]]},"reference":[{"key":"S1120962300012464_ref015","volume-title":"A.Ge.Me.Ge.","author":"Salzano","year":"1967"},{"key":"S1120962300012464_ref021","first-page":"429","article-title":"Selection, gene migration and polymorphic stability in a U. S. White and Negro population","volume":"15","author":"Workman","year":"1963","journal-title":"Amer. J. Hum. Genet."},{"key":"S1120962300012464_ref018","first-page":"401","article-title":"Abnormal hemoglobins in a Brazilian Negro population","volume":"14","author":"Tondo","year":"1962","journal-title":"Amer. J. Hum. Genet."},{"key":"S1120962300012464_ref020","first-page":"289","article-title":"G-6-PD deficiency in red cells. Incidence in The Cura\u00e7ao population, its clinical and genetic aspects","volume":"27","author":"Van der Sar","year":"1964","journal-title":"Enzymologia"},{"key":"S1120962300012464_ref007","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-56-5-765"},{"key":"S1120962300012464_ref013","first-page":"9","article-title":"Blood groups and gene flow in Negroes from Southern Brazil","volume":"13","author":"Salzano","year":"1963","journal-title":"Acta Genet."},{"key":"S1120962300012464_ref006","first-page":"21","article-title":"Skin colour in Southern Brazilian populations","volume":"39","author":"Harrison","year":"1967","journal-title":"Hum. Biol."},{"key":"S1120962300012464_ref003","volume-title":"The Metabolic Basis of Inherited Disease","author":"Beutler","year":"1965"},{"key":"S1120962300012464_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(63)91626-X"},{"key":"S1120962300012464_ref011","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1962.tb01316.x"},{"key":"S1120962300012464_ref001","first-page":"95","article-title":"Defici\u00eancia de G-6-PD e lepra","volume":"18","author":"Beiguelman","year":"1966","journal-title":"Ci\u00eancia e Cultura"},{"key":"S1120962300012464_ref010","first-page":"61","article-title":"Hereditary and acquired blood factors in the Negroid population of Surinam. II. The incidence of haemoglobin anomalies and the deficiency of G-6-PD","volume":"1","author":"Pik","year":"1965","journal-title":"Trop. Geogr. Med."},{"key":"S1120962300012464_ref019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1963.tb01329.x"},{"key":"S1120962300012464_ref005","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1182\/blood.V20.5.591.591","article-title":"A simple method for detection of erythrocyte G-6-PD deficiency (G-6-PD spot test)","volume":"20","author":"Fairbanks","year":"1962","journal-title":"Blood"},{"key":"S1120962300012464_ref004","first-page":"420","article-title":"Biochemical polymorphic traits in a U.S. White and Negro population","volume":"15","author":"Cooper","year":"1963","journal-title":"Amer. J. Hum. Genet."},{"key":"S1120962300012464_ref014","first-page":"116","article-title":"The dynamics of the Gc polymorphism in a Brazilian population","volume":"15","author":"Salzano","year":"1965","journal-title":"Acta Genet."},{"key":"S1120962300012464_ref012","first-page":"21","article-title":"Incidence of G-6-PD deficiency in Egypt","volume":"18","author":"Ragab","year":"1966","journal-title":"Amer. J. Hum. Genet."},{"key":"S1120962300012464_ref002","volume-title":"The Metabolic Basis of Inherited Disease","author":"Beutler","year":"1960"},{"key":"S1120962300012464_ref016","first-page":"41","article-title":"G-6-PD deficiency among certain Puerto Rican groups","volume":"53","author":"Suarez","year":"1961","journal-title":"Bol. Asoc. Med. Puerto Rico."},{"key":"S1120962300012464_ref009","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1542\/peds.26.2.285","article-title":"Activity of G-6-PD in erythrocytes of patients with various abnormal hemoglobins","volume":"26","author":"Naylor","year":"1960","journal-title":"Pediatrics"},{"key":"S1120962300012464_ref008","first-page":"60","article-title":"Evidence for heterogeneity among subjects with G-6-PD deficiency","volume":"32","author":"Marks","year":"1961","journal-title":"Abstract, 2nd Internat. Congr. Hum. Genet., Excerpta Med. Int. Congr. Series"}],"container-title":["Acta geneticae medicae et gemellologiae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1120962300012464","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T23:01:32Z","timestamp":1656889292000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1120962300012464\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,10]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1968,10]]}},"alternative-id":["S1120962300012464"],"URL":"https:\/\/doi.org\/10.1017\/s1120962300012464","relation":{},"ISSN":["1120-9623","2059-6316"],"issn-type":[{"value":"1120-9623","type":"print"},{"value":"2059-6316","type":"electronic"}],"subject":[],"published":{"date-parts":[[1968,10]]}}}