{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T06:54:55Z","timestamp":1648796095057},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"unspecified","delay-in-days":22127,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta genet. med. gemellol."],"published-print":{"date-parts":[[1954,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Heberden's nodes or osteoarthritis of the finger joints are described in two identical twins. The appearance of the hands and the bone changes in individual joints as shown by radiographs are remarkably alike. That the twins are identical is indicated by agreement of eye color, hair on the fingers, tasting of phenylthiocarbamide and of 8 blood groups. Evidence of a tendency to mirror imaging in the distribution of the disease among the fingers is seen.<\/jats:p><jats:p>Osteoarthritis of the fingers occurs in these cases in the apparent absence of manifestations of osteoarthritis in other joints. Heberden's nodes is an hereditary disease but this seems to be the first description published of its occurrence in twins.<\/jats:p>","DOI":"10.1017\/s112096230002151x","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T09:41:17Z","timestamp":1469612477000},"page":"84-92","source":"Crossref","is-referenced-by-count":0,"title":["Heberden's nodes: concordant osteoarthritis of the fingers in identical twins"],"prefix":"10.1017","volume":"3","author":[{"given":"Robert M.","family":"Stecher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,8,1]]},"reference":[{"key":"S112096230002151X_ref011","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-194702000-00009"},{"key":"S112096230002151X_ref005","first-page":"409","article-title":"Heberden's Nodes; Their Relation to Other Degenerative Joint Diseases","volume":"27","author":"Stecher","year":"1946","journal-title":"Archives of Physical Medicine"},{"key":"S112096230002151X_ref003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM194002222220802"},{"key":"S112096230002151X_ref001","first-page":"518","volume-title":"Commentaries on the History and Cure of Diseases","author":"Heberden","year":"1803"},{"key":"S112096230002151X_ref009","first-page":"326","article-title":"Heberden's Nodes, VII; The Roentgenological and Clinical Appearance of Degenerative Joint Disease of the Fingers","volume":"59","author":"Stecher","year":"1948","journal-title":"American Journal of Roentgenology and Radium Therapy"},{"key":"S112096230002151X_ref004","first-page":"301","article-title":"Heberden's Nodes; Heredity in Hypertrophic Arthritis of the Finger Joints","volume":"201","author":"Steche","year":"1941","journal-title":"American Journal of Medical Sciences"},{"key":"S112096230002151X_ref008","first-page":"1193","article-title":"Heberden's Nodes; The Relationship of the Menopause to Degenerative Joint Disease of the Fingers","volume":"34","author":"Stecher","year":"1949","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"S112096230002151X_ref006","first-page":"687","article-title":"Heberden's Nodes, 4; The Association of Hypertension and Obesity to Degenerative Joint Disease of the Fingers","volume":"31","author":"Stecher","year":"1946","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"S112096230002151X_ref010","doi-asserted-by":"publisher","DOI":"10.1172\/JCI101540"},{"key":"S112096230002151X_ref002","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4751.181"},{"key":"S112096230002151X_ref007","first-page":"310","article-title":"Nodulos de Heberden","volume":"3","author":"Stecher","year":"1949","journal-title":"Revista Espanola de Reumatismo"}],"container-title":["Acta geneticae medicae et gemellologiae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S112096230002151X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T06:06:22Z","timestamp":1559887582000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S112096230002151X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1954,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1954,1]]}},"alternative-id":["S112096230002151X"],"URL":"https:\/\/doi.org\/10.1017\/s112096230002151x","relation":{},"ISSN":["1120-9623","2059-6316"],"issn-type":[{"value":"1120-9623","type":"print"},{"value":"2059-6316","type":"electronic"}],"subject":[],"published":{"date-parts":[[1954,1]]}}}