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Online cognitive behavioural therapy (iCBT) programmes provide scalable access to psychological interventions, although the effectiveness of iCBT for OCD during COVID-19 has not been evaluated.<\/jats:p><\/jats:sec><jats:sec id=\"S1352465821000448_as2\"><jats:title>Aim:<\/jats:title><jats:p>This study investigated the uptake and effectiveness of iCBT for OCD (both self- and clinician-guided courses) during the first 8 months of the pandemic in Australia (March to October 2020) and compared outcomes with the previous year.<\/jats:p><\/jats:sec><jats:sec id=\"S1352465821000448_as3\"><jats:title>Method:<\/jats:title><jats:p>1,343 adults (824\/1343 (61.4%) female, mean age 33.54 years, <jats:italic>SD<\/jats:italic> = 12.00) commenced iCBT for OCD (1061 during the pandemic and 282 in the year before) and completed measures of OCD (Dimensional Obsessive-Compulsive Scale) and depression (Patient Health Questionaire-9) symptom severity, psychological distress (Kessler-10), and disability (WHO Disability Assessment Schedule) pre- and post-treatment.<\/jats:p><\/jats:sec><jats:sec id=\"S1352465821000448_as4\"><jats:title>Results:<\/jats:title><jats:p>During COVID-19, there was a 522% increase in monthly course registrations compared with the previous year, with peak uptake observed between April and June 2020 (a 1191% increase compared with April to June 2019). OCD and depression symptom severity were similar for the COVID and pre-COVID groups, although COVID-19 participants were more likely to enrol in self-guided courses (versus clinician-guided). In both pre- and during-COVID groups, the OCD iCBT course was associated with medium effect size reductions in OCD (<jats:italic>g<\/jats:italic> = 0.65\u20130.68) and depression symptom severity (<jats:italic>g<\/jats:italic> = 0.56\u20130.65), medium to large reductions in psychological distress (<jats:italic>g<\/jats:italic> = 0.77\u20130.83) and small reductions in disability (<jats:italic>g<\/jats:italic> = 0.35\u2013.50).<\/jats:p><\/jats:sec><jats:sec id=\"S1352465821000448_as5\"><jats:title>Conclusion:<\/jats:title><jats:p>Results demonstrate the considerable uptake of online psychological services for those experiencing symptoms of OCD during COVID-19 and highlight the scalability of effective digital mental health services.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1352465821000448","type":"journal-article","created":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T09:50:11Z","timestamp":1636537811000},"page":"219-236","source":"Crossref","is-referenced-by-count":14,"title":["COVID-19 related differences in the uptake and effects of internet-based cognitive behavioural therapy for symptoms of obsessive-compulsive disorder"],"prefix":"10.1017","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1595-9850","authenticated-orcid":false,"given":"Ian","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Millard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hila","family":"Haskelberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Hobbs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Luu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1118-4055","authenticated-orcid":false,"given":"Alison","family":"Mahoney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,11,10]]},"reference":[{"key":"S1352465821000448_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocrd.2019.100485"},{"key":"S1352465821000448_ref82","doi-asserted-by":"publisher","DOI":"10.1016\/S2589-7500(20)30224-7"},{"key":"S1352465821000448_ref97","doi-asserted-by":"publisher","DOI":"10.1016\/j.invent.2015.05.003"},{"key":"S1352465821000448_ref80","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.113310"},{"key":"S1352465821000448_ref87","volume-title":"Measuring health and disability: manual for WHO disability assessment schedule WHODAS 2.0","author":"\u00dcst\u00fcn","year":"2010"},{"key":"S1352465821000448_ref90","volume-title":"Cognitive Therapy of Anxiety Disorders: A Practice Manual and Conceptual Guide","author":"Wells","year":"1997"},{"key":"S1352465821000448_ref74","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7967(99)00049-2"},{"key":"S1352465821000448_ref37","doi-asserted-by":"publisher","DOI":"10.1017\/S1754470X20000318"},{"key":"S1352465821000448_ref33","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(20)30168-1"},{"key":"S1352465821000448_ref59","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.11.093"},{"key":"S1352465821000448_ref19","unstructured":"Centers for Disease Control and Prevention (2020). 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