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Psychother."],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1352465824000444_as1\"><jats:title>Background:<\/jats:title><jats:p>Cognitive therapy for PTSD (CT-PTSD) is an efficacious treatment for children and adolescents with post-traumatic stress disorder (PTSD) following single incident trauma, but there is a lack of evidence relating to this approach for youth with PTSD following exposure to multiple traumatic experiences.<\/jats:p><\/jats:sec><jats:sec id=\"S1352465824000444_as2\"><jats:title>Aims:<\/jats:title><jats:p>To assess the safety, acceptability and feasibility of CT-PTSD for youth following multiple trauma, and obtain a preliminary estimate of its pre\u2013post effect size.<\/jats:p><\/jats:sec><jats:sec id=\"S1352465824000444_as3\"><jats:title>Method:<\/jats:title><jats:p>Nine children and adolescents (aged 8\u201317 years) with multiple-trauma PTSD were recruited to a case series of CT-PTSD. Participants completed a structured interview and mental health questionnaires at baseline, post-treatment and 6-month follow-up, and measures of treatment credibility, therapeutic alliance, and mechanisms proposed to underpin treatment response. A developmentally adjusted algorithm for diagnosing PTSD was used.<\/jats:p><\/jats:sec><jats:sec id=\"S1352465824000444_as4\"><jats:title>Results:<\/jats:title><jats:p>No safety concerns or adverse effects were recorded. Suicidal ideation reduced following treatment. No participants withdrew from treatment or from the study. CT-PTSD was rated as highly credible. Participants reported strong working alliances with their therapists. Data completion was good at post-treatment (<jats:italic>n<\/jats:italic>=8), but modest at 6-month follow-up (<jats:italic>n<\/jats:italic>=6). Only two participants met criteria for PTSD (developmentally adjusted algorithm) at post-treatment. A large within-subjects treatment effect was observed post-treatment and at follow up for PTSD severity (using self-report questionnaire measures; <jats:italic>d<\/jats:italic>s&gt;1.65) and general functioning (CGAS; <jats:italic>d<\/jats:italic>s&lt;1.23). Participants showed reduced anxiety and depression symptoms at post-treatment and follow-up (RCADS-C; <jats:italic>d<\/jats:italic>s&gt;.57).<\/jats:p><\/jats:sec><jats:sec id=\"S1352465824000444_as5\"><jats:title>Conclusions:<\/jats:title><jats:p>These findings suggest that CT-PTSD is a safe, acceptable and feasible treatment for children with multiple-trauma PTSD, which warrants further evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1352465824000444","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T11:59:58Z","timestamp":1734695998000},"page":"47-62","source":"Crossref","is-referenced-by-count":0,"title":["Cognitive therapy for PTSD following multiple-trauma exposure in children and adolescents: a case series"],"prefix":"10.1017","volume":"53","author":[{"given":"Charlotte","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine E. 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