{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T19:50:59Z","timestamp":1774900259396,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2002,11,13]],"date-time":"2002-11-13T00:00:00Z","timestamp":1037145600000},"content-version":"unspecified","delay-in-days":12,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Neuropsychol Soc"],"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:p>Rapid eye movement (REM) sleep behavior disorder (RBD) is a \nsleep disturbance that commonly occurs in Dementia with Lewy \nbodies (DLB). Retrospective examination of DLB course has shown \nthat RBD and cognitive decline may precede the onset of \nparkinsonism and visual hallucinations. Therefore, some patients \nwith DLB may initially present with dementia and RBD, but would \nnot meet current formal criteria for probable DLB at that time. \nThe purpose of this study is to determine whether patients with \ndementia and RBD, who do not have parkinsonism or visual \nhallucinations, have cognitive profiles that can be distinguished \nfrom autopsy-confirmed definite AD, but not from clinically \nprobable DLB. If so, this would support the hypothesis that \nthe presence of RBD and dementia, as the only presenting symptoms, \nreflects the early manifestation of DLB. Results show that early \ndementia in probable DLB and dementia with RBD are \nneuropsychologically indistinguishable. Both groups differ from \ndefinite AD of a similar early stage with significantly worse \nvisual perceptual organization, sequencing and letter fluency \nbut significantly better confrontation naming and verbal memory. \nIn addition, follow-up data from a subset of patients with dementia \nand RBD reveal the subsequent development of parkinsonism or \nhallucinations 1 to 6 years later. Results indicate that the \npresentation of dementia and RBD is suggestive of underlying \nLewy body disease and not Alzheimer's disease. This provides \nfurther evidence in support of including RBD as one of the core \ndiagnostic features of DLB. (<jats:italic>JINS<\/jats:italic>, 2002, <jats:italic>8<\/jats:italic>, 907\u2013914.)<\/jats:p>","DOI":"10.1017\/s1355617702870047","type":"journal-article","created":{"date-parts":[[2002,11,13]],"date-time":"2002-11-13T23:26:37Z","timestamp":1037229997000},"page":"907-914","source":"Crossref","is-referenced-by-count":94,"title":["Dementia with Lewy bodies may present as dementia and REM \nsleep behavior disorder without parkinsonism or hallucinations"],"prefix":"10.1017","volume":"8","author":[{"given":"TANIS J.","family":"FERMAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BRADLEY F.","family":"BOEVE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GLENN E.","family":"SMITH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL H.","family":"SILBER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOHN A.","family":"LUCAS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NEILL R.","family":"GRAFF-RADFORD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DENNIS W.","family":"DICKSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOSEPH E.","family":"PARISI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RONALD C.","family":"PETERSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROBERT J.","family":"IVNIK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2002,11,13]]},"container-title":["Journal of the International Neuropsychological Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1355617702870047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T00:26:48Z","timestamp":1557188808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1355617702870047\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2002,11]]}},"alternative-id":["S1355617702870047"],"URL":"https:\/\/doi.org\/10.1017\/s1355617702870047","relation":{},"ISSN":["1355-6177","1469-7661"],"issn-type":[{"value":"1355-6177","type":"print"},{"value":"1469-7661","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11]]}}}