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Forty-four boys (21 ADHD, 23 control) and 42 girls (21 ADHD, 21 control), ages 8\u201313 years, participated. Sulcal\u2013gyral landmarks were used to manually delimit functionally relevant regions within the frontal lobe: primary motor cortex, anterior cingulate, deep white matter, premotor regions [supplementary motor complex (SMC), frontal eye field, lateral premotor cortex (LPM)], and prefrontal cortex (PFC) regions [medial PFC, dorsolateral PFC (DLPFC), inferior PFC, lateral orbitofrontal cortex (OFC), and medial OFC]. Compared to sex-matched controls, boys <jats:italic>and<\/jats:italic> girls with ADHD showed reduced volumes (gray and white matter) in the left SMC. Conversely, girls (but not boys) with ADHD showed reduced gray matter volume in left LPM; while boys (but not girls) with ADHD showed reduced white matter volume in left medial PFC. Reduced left SMC gray matter volumes predicted increased go\/no\u2013go commission rate in children with ADHD. Reduced left LPM gray matter volumes predicted increased go\/no\u2013go variability, but only among girls with ADHD. Results highlight different patterns of anomalous frontal lobe development among boys and girls with ADHD beyond that detected by measuring whole lobar volumes. (<jats:italic>JINS<\/jats:italic>, 2011, <jats:italic>17<\/jats:italic>, 1047\u20131057)<\/jats:p>","DOI":"10.1017\/s1355617711001056","type":"journal-article","created":{"date-parts":[[2011,9,19]],"date-time":"2011-09-19T09:12:44Z","timestamp":1316423564000},"page":"1047-1057","source":"Crossref","is-referenced-by-count":45,"title":["Comprehensive Examination of Frontal Regions in Boys and Girls with Attention-Deficit\/Hyperactivity Disorder"],"prefix":"10.1017","volume":"17","author":[{"given":"E. 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