{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:31:11Z","timestamp":1790339471832,"version":"4.1.0"},"reference-count":53,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T00:00:00Z","timestamp":1538438400000},"content-version":"unspecified","delay-in-days":31,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Neuropsychol Soc"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    Although subjective cognitive complaints (SCC) are an integral component of the diagnostic criteria for mild cognitive impairment (MCI), previous findings indicate they may not accurately reflect cognitive ability. Within the Alzheimer\u2019s Disease Neuroimaging Initiative, we investigated longitudinal change in the discrepancy between self- and informant-reported SCC across empirically derived subtypes of MCI and normal control (NC) participants.\n                    <jats:bold>Methods:<\/jats:bold>\n                    Data were obtained for 353 MCI participants and 122 \u201crobust\u201d NC participants. Participants were classified into three subtypes at baseline\n                    <jats:italic>via<\/jats:italic>\n                    cluster analysis: amnestic MCI, mixed MCI, and cluster-derived normal (CDN), a presumptive false-positive group who performed within normal limits on neuropsychological testing. SCC at baseline and two annual follow-up visits were assessed\n                    <jats:italic>via<\/jats:italic>\n                    the Everyday Cognition Questionnaire (ECog), and discrepancy scores between self- and informant-report were calculated. Analysis of change was conducted using analysis of covariance.\n                    <jats:bold>Results:<\/jats:bold>\n                    The amnestic and mixed MCI subtypes demonstrated increasing ECog discrepancy scores over time. This was driven by an increase in informant-reported SCC, which corresponded to participants\u2019 objective cognitive decline, despite stable self-reported SCC. Increasing unawareness was associated with cerebrospinal fluid Alzheimer\u2019s disease biomarker positivity and progression to Alzheimer\u2019s disease. In contrast, CDN and NC groups over-reported cognitive difficulty and demonstrated normal cognition at all time points.\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    MCI participants\u2019 discrepancy scores indicate progressive underappreciation of their evolving cognitive deficits. Consistent over-reporting in the CDN and NC groups despite normal objective cognition suggests that self-reported SCC do not predict impending cognitive decline. Results demonstrate that self-reported SCC become increasingly misleading as objective cognitive impairment becomes more pronounced. (\n                    <jats:italic>JINS<\/jats:italic>\n                    , 2018,\n                    <jats:italic>24<\/jats:italic>\n                    , 842\u2013853)\n                  <\/jats:p>","DOI":"10.1017\/s1355617718000486","type":"journal-article","created":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T10:52:00Z","timestamp":1538477520000},"page":"842-853","source":"Crossref","is-referenced-by-count":82,"title":["Increasing Inaccuracy of Self-Reported Subjective Cognitive Complaints Over 24 Months in Empirically Derived Subtypes of Mild Cognitive Impairment"],"prefix":"10.1017","volume":"24","author":[{"given":"Emily C.","family":"Edmonds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra J.","family":"Weigand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4277-8876","authenticated-orcid":false,"given":"Kelsey 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