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Reports have identified CNS involvement in CMTX, but no systematic study of cognitive function has been published.<\/jats:p><\/jats:sec><jats:sec id=\"S1355617719001188_as2\"><jats:title>Methods:<\/jats:title><jats:p>We assessed 24 CMTX patients (13 males; 9<jats:italic>GJB1<\/jats:italic>mutations) with a comprehensive neuropsychological battery, including tests of memory, language, and executive functions.<\/jats:p><\/jats:sec><jats:sec id=\"S1355617719001188_as3\"><jats:title>Results:<\/jats:title><jats:p>No differences in cognitive performance were observed between males and females. A case-by-case investigation revealed selective deficits in individual patients. One subgroup (29%) demonstrated executive abnormalities; and a non-overlapping subgroup (29%), prominent reading (decoding) abnormalities.<\/jats:p><\/jats:sec><jats:sec id=\"S1355617719001188_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>The present data provide evidence for cognitive deficits in CMTX. Emerging neuropsychological patterns are also discussed.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1355617719001188","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T08:48:38Z","timestamp":1579250918000},"page":"294-302","source":"Crossref","is-referenced-by-count":6,"title":["Evidence for Cognitive Deficits in X-Linked Charcot-Marie-Tooth 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