{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T05:34:50Z","timestamp":1775021690276,"version":"3.50.1"},"reference-count":50,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"unspecified","delay-in-days":2,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Neuropsychol Soc"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1355617724000304_as1\"><jats:title>Objective:<\/jats:title><jats:p>High-definition transcranial direct current stimulation (HD-tDCS) has the potential to improve cognitive functioning following neurological injury and in neurodegenerative conditions. In this case report, we present the first use of HD-tDCS in a person with severe anterograde amnesia following carbon monoxide poisoning.<\/jats:p><\/jats:sec><jats:sec id=\"S1355617724000304_as2\"><jats:title>Method:<\/jats:title><jats:p>The participant underwent two rounds of HD-tDCS that were separated by 3 months (Round 1 = 30 sessions; Round 2 = 31 sessions). We used finite element modeling of the participant\u2019s structural MRI to develop an individualized montage that targeted multiple brain regions involved in memory encoding, as identified by Neurosynth.<\/jats:p><\/jats:sec><jats:sec id=\"S1355617724000304_as3\"><jats:title>Results:<\/jats:title><jats:p>Overall, the participant\u2019s objective cognitive functioning improved significantly following Round 1, declined during the 2 months without HD-tDCS, and again improved following Round 2. Subjective informant reports from family and medical personnel followed this same pattern of improvement following each round with a decline in between rounds. We also provide preliminary evidence of altered brain activity during a learning\/memory task using functional near-infrared spectroscopy, which may help establish the physiological effects of HD-tDCS in future work.<\/jats:p><\/jats:sec><jats:sec id=\"S1355617724000304_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Overall, these findings reinforce the potential value of HD-tDCS as a user-friendly method of enhancing cognition following anoxic\/hypoxic brain injury.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1355617724000304","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T05:21:36Z","timestamp":1733203296000},"page":"1015-1021","source":"Crossref","is-referenced-by-count":1,"title":["Personalized high-definition transcranial direct current stimulation improves cognition following carbon monoxide poisoning induced amnesia: A case 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