{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T12:41:13Z","timestamp":1772196073316,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Neuropsychol Soc"],"published-print":{"date-parts":[[1999,11]]},"abstract":"<jats:p>HIV infection often results in neuropsychological \n(NP) impairment. In order to assess the impact that HIV-related \nNP deficits may have on automobile driving, we evaluated \n68 HIV-seropositive drivers using an NP battery and two \nPC-based driving simulations. Thirty-two participants were \nclassified as NP impaired; most (72%) evidenced only mild \nimpairment, and none met criteria for HIV-associated dementia. \nAfter controlling for degree of immunosuppression and disease \nstage, NP-impaired participants failed a previously validated \ndriving simulation at a much higher rate than cognitively \nintact participants [OR = 5.3, 95% CI (1.7, 17.0), \n<jats:italic>p<\/jats:italic> = .006]. Similarly, on a simulation of \ncity driving, NP impaired participants were more likely \nto fail based upon the number of accidents [OR = 6.1, \n95% CI (1.5, 24.6), <jats:italic>p<\/jats:italic> = .01]. Simulator performance \nwas predicted by functioning in a number of NP domains, \nwith NP tests accounting for 13\u201330% of the variance \non the simulations. Although it would be premature to extrapolate \nthese findings to impairment in on-the-road driving, they \ndo argue for greater attention to the impact that even \nmild HIV-related NP deficits may have on driving skills. \n(<jats:italic>JINS<\/jats:italic>, 1999, <jats:italic>5<\/jats:italic>, 579\u2013592.)<\/jats:p>","DOI":"10.1017\/s1355617799577011","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:26:15Z","timestamp":1027761975000},"page":"579-592","source":"Crossref","is-referenced-by-count":106,"title":["The impact of HIV-related neuropsychological dysfunction \non driving behavior"],"prefix":"10.1017","volume":"5","author":[{"given":"THOMAS D.","family":"MARCOTTE","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROBERT K.","family":"HEATON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TANYA","family":"WOLFSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL J.","family":"TAYLOR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"OMAR","family":"ALHASSOON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KAIVON","family":"ARFAA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IGOR","family":"GRANT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"THE HNRC GROUP","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,11,1]]},"container-title":["Journal of the International Neuropsychological Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1355617799577011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T16:00:33Z","timestamp":1557417633000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1355617799577011\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1999,11]]}},"alternative-id":["S1355617799577011"],"URL":"https:\/\/doi.org\/10.1017\/s1355617799577011","relation":{},"ISSN":["1355-6177","1469-7661"],"issn-type":[{"value":"1355-6177","type":"print"},{"value":"1469-7661","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,11]]}}}