{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:46:06Z","timestamp":1780325166965,"version":"3.54.1"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2011,12,14]],"date-time":"2011-12-14T00:00:00Z","timestamp":1323820800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1368980011003235_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>The purpose was to examine the role of dietary patterns derived from factor analysis and their association with health and disease.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980011003235_abs2\" sec-type=\"general\"><jats:title>Design<\/jats:title><jats:p>Longitudinal population study, with measurement of diet (dietary history method), cardiovascular risk factors and a follow-up of 20 years for CHD incidence and 40 years for mortality.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980011003235_abs3\" sec-type=\"general\"><jats:title>Setting<\/jats:title><jats:p>Two population samples in rural villages in northern and central Italy.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980011003235_abs4\" sec-type=\"subjects\"><jats:title>Subjects<\/jats:title><jats:p>Men (<jats:italic>n<\/jats:italic> 1221) aged 45\u201364 years were examined and followed up.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980011003235_abs5\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>One of the factors identified with factor analysis, run on seventeen food groups, was converted into a factor score (Factor 2 score) and used as a possible predictor of morbid and fatal events. High values of Factor 2 score were characterized by higher consumption of bread, cereals (pasta), potatoes, vegetables, fish and oil and by lower consumption of milk, sugar, fruit and alcoholic beverages. In multivariate analysis, Factor 2 score (mean 0\u00b70061; <jats:sc>sd<\/jats:sc> 1\u00b73750) was inversely and significantly associated (hazard ratio for a 1 <jats:sc>sd<\/jats:sc> increase; 95% CI) with 20-year CHD incidence (0\u00b788; 0\u00b773, 0\u00b796) and 40-year mortality from CHD (0\u00b779; 0\u00b766, 0\u00b795), CVD (0\u00b787; 0\u00b778, 0\u00b796), cancer (0\u00b784; 0\u00b774, 0\u00b796) and all causes (0\u00b789; 0\u00b783, 0\u00b796), after adjustment for five other risk factors. Men in quintile 5 of Factor 2 score had a 4\u00b71 years longer life expectancy compared with men in quintile 1.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980011003235_abs6\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>A dietary pattern derived from factor analysis, and resembling the characteristics of the Mediterranean diet, was protective for the occurrence of various morbid and fatal events during 40 years of follow-up.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1368980011003235","type":"journal-article","created":{"date-parts":[[2011,12,14]],"date-time":"2011-12-14T09:40:59Z","timestamp":1323855659000},"page":"1232-1239","source":"Crossref","is-referenced-by-count":36,"title":["Factor analysis in the identification of dietary patterns and their predictive role in morbid and fatal events"],"prefix":"10.1017","volume":"15","author":[{"given":"Alessandro","family":"Menotti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adalberta","family":"Alberti-Fidanza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flaminio","family":"Fidanza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariapaola","family":"Lanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Fruttini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2011,12,14]]},"reference":[{"key":"S1368980011003235_ref22","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.771881"},{"key":"S1368980011003235_ref17","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.22.2461"},{"key":"S1368980011003235_ref3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.7018.1457"},{"key":"S1368980011003235_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2004.03.015"},{"key":"S1368980011003235_ref15","doi-asserted-by":"publisher","DOI":"10.1079\/BJN20061824"},{"key":"S1368980011003235_ref38","first-page":"245","volume-title":"Readings and Understanding Multivariate Analysis","author":"Bryant","year":"1995"},{"key":"S1368980011003235_ref28","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyp191"},{"key":"S1368980011003235_ref7","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007529206050"},{"key":"S1368980011003235_ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114507704981"},{"key":"S1368980011003235_ref37","volume-title":"Computer Aided Multivariate Analysis","author":"Afifi","year":"1990"},{"key":"S1368980011003235_ref31","article-title":"The association of the Mediterranean Adequacy Index with fatal coronary events in an Italian middle-aged male population followed for 40 years","author":"Menotti","year":"2010","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"S1368980011003235_ref39","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1344"},{"key":"S1368980011003235_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0939-4753(04)80052-8"},{"key":"S1368980011003235_ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.12.1433"},{"key":"S1368980011003235_ref32","first-page":"1","article-title":"Coronary heart disease in seven countries","volume":"41","author":"Keys","year":"1970","journal-title":"Circulation"},{"key":"S1368980011003235_ref8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601360"},{"key":"S1368980011003235_ref4","first-page":"408","article-title":"Relationship between eating patterns meeting recommendations and subsequent mortality in 20 years","volume":"49","author":"Farchi","year":"1995","journal-title":"Eur J Clin Nutr"},{"key":"S1368980011003235_ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3841.2009.01268.x"},{"key":"S1368980011003235_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2008.06.005"},{"key":"S1368980011003235_ref23","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1093\/ajcn\/87.5.1414","article-title":"Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality","volume":"87","author":"Brunner","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"S1368980011003235_ref36","volume-title":"Factor Analysis. 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