{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:47:00Z","timestamp":1790624820421,"version":"4.1.0"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2012,11,27]],"date-time":"2012-11-27T00:00:00Z","timestamp":1353974400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1368980012004697_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>To assess whether nutritional deficiency increases susceptibility to arsenic-related health effects.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980012004697_abs2\" sec-type=\"general\"><jats:title>Design<\/jats:title><jats:p>Assessment of nutrition was based on a 24 h recall method of all dietary constituents.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980012004697_abs3\" sec-type=\"general\"><jats:title>Setting<\/jats:title><jats:p>Epidemiological cross-sectional study was conducted in an arsenic-endemic area of West Bengal with groundwater arsenic contamination.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980012004697_abs4\" sec-type=\"subjects\"><jats:title>Subjects<\/jats:title><jats:p>The study was composed of two groups \u2013 Group 1 (cases,<jats:italic>n<\/jats:italic>108) exhibiting skin lesions and Group 2 (exposed controls,<jats:italic>n<\/jats:italic>100) not exhibiting skin lesions \u2013 age- and sex-matched and having similar arsenic exposure through drinking water and arsenic levels in urine and hair.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980012004697_abs5\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Both groups belonged to low socio-economic strata (Group 1 significantly poorer,<jats:italic>P<\/jats:italic>&lt; 0\u00b701) and had low BMI (prevalence of BMI &lt; 18\u00b75 kg\/m<jats:sup>2<\/jats:sup>: in 38 % in Group 1 and 27 % in Group 2). Energy intake was below the Recommended Daily Allowance (set by the Indian Council of Medical Research) in males and females in both groups. Increased risk of arsenical skin lesions was found for those in the lowest quintile of protein intake (<jats:italic>v<\/jats:italic>. highest quintile: OR = 4\u00b760, 95 % CI 1\u00b736, 15\u00b750 in males; OR = 5\u00b762, 95 % CI 1\u00b719, 34\u00b757 in females). Significantly lower intakes of energy, protein, thiamin, niacin, Mg, Zn and choline were observed in both males and females of Group 1 compared with Group 2. Significantly lower intakes of carbohydrate, riboflavin, niacin and Cu were also observed in female cases with skin lesions compared with non-cases.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980012004697_abs6\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>Deficiencies of Zn, Mg and Cu, in addition to protein, B vitamins and choline, are found to be associated with arsenical skin lesions in West Bengal.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1368980012004697","type":"journal-article","created":{"date-parts":[[2012,11,27]],"date-time":"2012-11-27T05:01:33Z","timestamp":1353992493000},"page":"1644-1655","source":"Crossref","is-referenced-by-count":44,"title":["Nutritional deficiency and arsenical manifestations: a perspective study in an arsenic-endemic region of West Bengal, India"],"prefix":"10.1017","volume":"16","author":[{"given":"Debasree","family":"Deb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anirban","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aloke","family":"Ghose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arabinda","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunal K","family":"Majumdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debendra N","family":"Guha Mazumder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2012,11,27]]},"reference":[{"key":"S1368980012004697_ref22","volume-title":"Nutrition Monitoring and Assessment","author":"Gopaldas","year":"1987"},{"key":"S1368980012004697_ref18","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/003685049908200104","article-title":"Methylation of inorganic arsenic in different mammalian species and population groups","volume":"82","author":"Vahter","year":"1999","journal-title":"Sci Prog"},{"key":"S1368980012004697_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-0348-6540-1_14"},{"key":"S1368980012004697_ref32","doi-asserted-by":"publisher","DOI":"10.3109\/15563659809162616"},{"key":"S1368980012004697_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2005.10.006"},{"key":"S1368980012004697_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/B978-044451441-7\/50010-5"},{"key":"S1368980012004697_ref1","volume-title":"Arsenic and Arsenic Compounds. 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