{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T02:02:41Z","timestamp":1782698561682,"version":"3.54.5"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2013,3,11]],"date-time":"2013-03-11T00:00:00Z","timestamp":1362960000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1368980013000608_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>To describe the prevalence of iron depletion (ID), iron-deficiency anaemia (IDA) and risk of haemoconcentration during pregnancy and at delivery and to assess the influence of initial Fe stores and Fe supplementation on that prevalence.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980013000608_abs2\" sec-type=\"general\"><jats:title>Design<\/jats:title><jats:p>Longitudinal study.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980013000608_abs3\" sec-type=\"general\"><jats:title>Setting<\/jats:title><jats:p>Hospital Universitari Sant Joan de Reus (Catalonia, Spain).<\/jats:p><\/jats:sec><jats:sec id=\"S1368980013000608_abs4\" sec-type=\"subjects\"><jats:title>Subjects<\/jats:title><jats:p>Two hundred and eighty-five pregnant women. Serum ferritin and Hb were measured in the first, second and third trimesters and at delivery. Women were classified according to initial Fe stores as ID or no ID (serum ferritin \u226512 \u03bcg\/l) and according to Fe supplement use as supplemented or non-supplemented.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980013000608_abs5\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Initial ID was 16\u00b72 %. At delivery, 45\u00b77 % had ID, 13\u00b75 % IDA and 13\u00b73 % had risk of haemoconcentration. Initial ID and non-supplemented groups had significantly higher prevalences of ID and IDA and lower risk of haemoconcentration at delivery than the other groups. In the multiple logistic models, no initial ID and Fe supplementation exerted a protective effect against ID at delivery (adjusted OR = 0\u00b728; 95 % CI 0\u00b713, 0\u00b758 and adjusted OR = 0\u00b739; 95 % CI 0\u00b722, 0\u00b769, respectively). Moderate Fe supplementation did not seem to clearly prevent IDA (adjusted OR = 0\u00b791; 95 % CI 0\u00b742, 1\u00b796) or to enhance the haemoconcentration (adjusted OR = 1\u00b742; 95 % CI 0\u00b758, 3\u00b750).<\/jats:p><\/jats:sec><jats:sec id=\"S1368980013000608_abs6\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>The prevalence of ID and IDA was high in late pregnancy in healthy pregnant women, particularly in those with initial ID and\/or those not taking supplements. Starting pregnancy with no ID and\/or taking moderate Fe supplementation decreased the likelihood of ID at delivery. The risk of haemoconcentration was high at delivery, but did not seem to be promoted by Fe supplementation. Further research is necessary to determine the most appropriate nutritional advice for pregnant women.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1368980013000608","type":"journal-article","created":{"date-parts":[[2013,3,11]],"date-time":"2013-03-11T09:53:45Z","timestamp":1362995625000},"page":"1371-1378","source":"Crossref","is-referenced-by-count":19,"title":["Prevalence of iron deficiency states and risk of haemoconcentration during pregnancy according to initial iron stores and iron supplementation"],"prefix":"10.1017","volume":"16","author":[{"given":"Victoria","family":"Arija","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blanca","family":"Ribot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00faria","family":"Aranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2013,3,11]]},"reference":[{"key":"S1368980013000608_ref31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2011.00429.x"},{"key":"S1368980013000608_ref36","first-page":"290","volume-title":"Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc","year":"2001"},{"key":"S1368980013000608_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaceta.2009.09.014"},{"key":"S1368980013000608_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2011.01.042"},{"key":"S1368980013000608_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.12.006"},{"key":"S1368980013000608_ref38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08952.x"},{"key":"S1368980013000608_ref34","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00610.x"},{"key":"S1368980013000608_ref3","volume-title":"Worldwide Prevalence of Anaemia 1993\u20132005. WHO Global Database on Anaemia","year":"2008"},{"key":"S1368980013000608_ref15","first-page":"1","article-title":"Recommendations to prevent and control iron deficiency in the United States","volume":"47","year":"1998","journal-title":"MMWR Recomm Rep"},{"key":"S1368980013000608_ref28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2009.00156.x"},{"key":"S1368980013000608_ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-011-1279-z"},{"key":"S1368980013000608_ref30","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.5.1218"},{"key":"S1368980013000608_ref33","article-title":"Predictors of haemoconcentration at delivery: association with low birth weight","author":"Aranda","year":"2012","journal-title":"Eur J Nutr"},{"key":"S1368980013000608_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9120(00)00064-3"},{"key":"S1368980013000608_ref24","first-page":"446","article-title":"Prevalence of iron deficiency in the female working population in the reproductive age","volume":"196","author":"Bermejo","year":"1996","journal-title":"Rev Clin Esp"},{"key":"S1368980013000608_ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.1995.tb01485.x"},{"key":"S1368980013000608_ref12","first-page":"21","article-title":"Four factor index of social status","volume":"8","author":"Hollingshead","year":"2011","journal-title":"Yale J Sociol"},{"key":"S1368980013000608_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-006-0141-1"},{"key":"S1368980013000608_ref21","doi-asserted-by":"publisher","DOI":"10.1017\/S000711450800679X"},{"key":"S1368980013000608_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/72.1.257S"},{"key":"S1368980013000608_ref4","first-page":"CD004736","article-title":"Effects and safety of preventive oral iron or iron+folic supplementation for women during pregnancy","author":"Pena-Rosas","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"S1368980013000608_ref6","first-page":"741","article-title":"High and low hemoglobin levels during pregnancy: differential risks for preterm birth and small for gestational age","volume":"96","author":"Scanlon","year":"2000","journal-title":"Obstet Gynecol"},{"key":"S1368980013000608_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.011"},{"key":"S1368980013000608_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2011.06.003"},{"key":"S1368980013000608_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/76.6.1392"},{"key":"S1368980013000608_ref11","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-0164"},{"key":"S1368980013000608_ref14","first-page":"1698","volume-title":"Tietz Textbook of Clinical Chemistry","author":"Fairbanks","year":"1999"},{"key":"S1368980013000608_ref17","first-page":"832","article-title":"Anthropometric nutritional evaluation of pregnant women and its relation with the product of the gestation","volume":"25","author":"Carrillo","year":"2010","journal-title":"Nutr Hosp"},{"key":"S1368980013000608_ref19","volume-title":"Pregnancy Nutrition Surveillance 2009 Report","author":"Reinold","year":"2011"},{"key":"S1368980013000608_ref20","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2011.187"},{"key":"S1368980013000608_ref22","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2010.086991"},{"key":"S1368980013000608_ref23","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01070308"},{"key":"S1368980013000608_ref25","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980009991054"},{"key":"S1368980013000608_ref26","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/78.4.773"},{"key":"S1368980013000608_ref29","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-008-0518-4"},{"key":"S1368980013000608_ref32","doi-asserted-by":"publisher","DOI":"10.1177\/1076029607304748"},{"key":"S1368980013000608_ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2011.07.041"},{"key":"S1368980013000608_ref37","first-page":"133","article-title":"Hemochromatosis: discovery of the HFE gene","volume":"109","author":"Bacon","year":"2012","journal-title":"Mo Med"}],"container-title":["Public Health Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1368980013000608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T20:47:02Z","timestamp":1556052422000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1368980013000608\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,11]]},"references-count":38,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S1368980013000608"],"URL":"https:\/\/doi.org\/10.1017\/s1368980013000608","relation":{},"ISSN":["1368-9800","1475-2727"],"issn-type":[{"value":"1368-9800","type":"print"},{"value":"1475-2727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,11]]}}}