{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T19:38:59Z","timestamp":1773344339713,"version":"3.50.1"},"reference-count":44,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2014,11,28]],"date-time":"2014-11-28T00:00:00Z","timestamp":1417132800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1368980014002572_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>To assess the potential contribution of foods fortified with folic acid (FA) to target population intakes when included as part of a healthy breakfast.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980014002572_abs2\" sec-type=\"general\"><jats:title>Design<\/jats:title><jats:p>Breakfast models aligned with the Spanish Dietary Guidelines were studied using the recommended, average and 95th percentile of serving sizes consumed by women of childbearing age. Food composition data were obtained from a database including FA analytical data from sixty-eight products and the Spanish food composition tables. Different scenarios were assessed with the inclusion of one, two or three FA-fortified products and with two different fortification levels: \u226433 \u00b5g\/serving (L1) and \u226570 \u00b5g\/serving (L4). FA contents provided by the different models for each scenario were compared with the Recommended Nutrient Intake (RNI) for folate and the Upper Level (UL) of intake for FA.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980014002572_abs3\" sec-type=\"general\"><jats:title>Setting<\/jats:title><jats:p>Madrid Region, Spain.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980014002572_abs4\" sec-type=\"subjects\"><jats:title>Subjects<\/jats:title><jats:p>Women aged 16\u201349 years were considered.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980014002572_abs5\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Overall, simulation of ten breakfast models and three scenarios of product inclusion accounted for 20\u201325 % of total daily energy recommendations for women. Unfortified breakfast models provided on average 4\u201323 % of the folate RNI. Inclusion of one L4 FA-fortified food contributed 20\u201360 % of the RNI. Fortified yoghurt and milk had the highest FA contents per serving. Scenarios with two or three fortified products delivered 40\u201380 % of the RNI. None of the evaluated models exceeded the FA UL.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980014002572_abs6\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>At existing levels of FA fortification, inclusion of fortified products as part of a regular breakfast meal could positively impact the nutritional quality of women\u2019s diet without involving a risk of excessive FA exposure.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1368980014002572","type":"journal-article","created":{"date-parts":[[2014,11,28]],"date-time":"2014-11-28T16:44:57Z","timestamp":1417193097000},"page":"1960-1968","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":7,"title":["Contribution of folic acid-fortified foods to fertile women\u2019s folate Recommended Nutrient Intake through breakfast simulation models"],"prefix":"10.1017","volume":"18","author":[{"given":"Mar\u00eda de Lourdes","family":"Samaniego-Vaesken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Alonso-Aperte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregorio","family":"Varela-Moreiras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,11,28]]},"reference":[{"key":"S1368980014002572_ref43","doi-asserted-by":"publisher","DOI":"10.1079\/PHN2001234"},{"key":"S1368980014002572_ref38","volume-title":"H\u00e1bitos alimentarios y consumo de alimentos en la poblaci\u00f3n infantil y juvenil espa\u00f1ola (1998\u20132000). 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(2004) Gu\u00eda de la Alimentaci\u00f3n Saludable. http:\/\/www.aesan.msc.es\/AESAN\/docs\/docs\/come_seguro_y_saludable\/guia_alimentacion2.pdf (accessed June 2013)."},{"key":"S1368980014002572_ref23","first-page":"228","volume-title":"Tablas de Composici\u00f3n de los Alimentos","author":"Moreiras","year":"2011"},{"key":"S1368980014002572_ref32","unstructured":"Ministerio de Sanidad, Servicios Sociales e Igualdad (2007) Campa\u00f1a de prevenci\u00f3n de la obesidad infantil \u2018\u00a1Despierta desayuna!\u2019 https:\/\/www.msssi.gob.es\/campannas\/campanas06\/obesidadInfant5.htm (accessed December 2013)."},{"key":"S1368980014002572_ref17","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2010.10719858"},{"key":"S1368980014002572_ref16","unstructured":"Varela-Moreiras G , \u00c1vila J , Cuadrado C et al. (2012) Valoraci\u00f3n Nutricional de la Dieta Espa\u00f1ola de acuerdo al Panel de Consumo Alimentario. http:\/\/www.fen.org.es\/imgPublicaciones\/30092012125258.pdf (accessed May 2013)."},{"key":"S1368980014002572_ref33","first-page":"1610","article-title":"Micronutrient recommendations and policies in Spain: the cases of iodine, folic acid and vitamin D","volume":"27","author":"Brito Garc\u00eda","year":"2012","journal-title":"Nutr Hosp"},{"key":"S1368980014002572_ref5","unstructured":"Flour Fortification Initiative (2013) Wheat Flour Fortification Status \u2013 May 2013. Map of Global Progress. 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(2014) Encuesta de Nutrici\u00f3n de la Comunidad de Madrid, ENUCAM 2009\u20132010. Documentos T\u00e9cnicos de Salud P\u00fablica, Comunidad de Madrid (In the Press)."},{"key":"S1368980014002572_ref13","doi-asserted-by":"publisher","DOI":"10.3945\/jn.112.164616"},{"key":"S1368980014002572_ref8","volume-title":"Evaluation of the Dutch Legislation on Food Fortification with Folic Acid and Vitamin D; Focus on Young Children","author":"Verkaik-Kloosterman","year":"2009"},{"key":"S1368980014002572_ref19","unstructured":"Samaniego-Vaesken ML (2013) Folic acid food fortification in Spain: food composition database, folic acid and folate analysis and predicted contribution to dietary reference intakes. 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Australian Food and Nutrition Monitoring Unit, The National Food and Nutrition Monitoring and Surveillance Project, The Commonwealth Department of Health and Aged Care. http:\/\/www.health.gov.au\/internet\/main\/publishing.nsf\/Content\/84026385A0EC6DC9CA256F190004C8E1\/$File\/folate.pdf (accessed May 2013)."},{"key":"S1368980014002572_ref1","volume-title":"The Biochemistry of Folic Acid and Related Pteridines","author":"Blakley","year":"1969"},{"key":"S1368980014002572_ref29","unstructured":"National Institute for Biological Standards and Control (2008) WHO International Standard Vitamin B12 And Serum Folate, NIBSC code: 03\/178 Instructions for use (Version 2.0, Dated 04\/04\/2008). http:\/\/www.nibsc.org\/documents\/ifu\/03-178.pdf (accessed February 2013)."},{"key":"S1368980014002572_ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000330776"},{"key":"S1368980014002572_ref10","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201000391"},{"key":"S1368980014002572_ref28","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/jaoac\/80.3.611","article-title":"Certification of nutrients in Standard Reference Material 1846: infant formula","volume":"80","author":"Sharpless","year":"1997","journal-title":"J AOAC Int"},{"key":"S1368980014002572_ref9","first-page":"459","article-title":"Folic acid fortified foods available in Spain: type of products, level of fortification and target population groups","volume":"24","author":"Samaniego-Vaesken","year":"2009","journal-title":"Nutr Hosp"},{"key":"S1368980014002572_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfca.2010.02.004"},{"key":"S1368980014002572_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2005.02.007"},{"key":"S1368980014002572_ref15","unstructured":"Ministerio de Agricultura, Pesca y Alimentaci\u00f3n MAGRAMA (2006) Qu\u00e9 desayunan los espa\u00f1oles? Observatorio del consumo y la distribuci\u00f3n alimentaria. http:\/\/www.marm.es\/es\/alimentacion\/temas\/consumo-y-comercializacion-y-distribucion-alimentaria\/desayuno_espanoles_tcm7-7939.pdf (accessed June 2013)."},{"key":"S1368980014002572_ref35","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2009.1213"},{"key":"S1368980014002572_ref31","doi-asserted-by":"publisher","DOI":"10.1159\/000066398"},{"key":"S1368980014002572_ref34","doi-asserted-by":"publisher","DOI":"10.1079\/PHN2005666"},{"key":"S1368980014002572_ref21","unstructured":"The European Parliament & The Council of the European Union (2011) Regulation (EU) No 1169\/2011 of the European Parliament and of the Council of 25 October 2011 on the provision of food information to consumers, amending Regulations (EC) No 1924\/2006 and (EC) No 1925\/2006 of the European Parliament and of the Council, and repealing Commission Directive 87\/250\/EEC, Council Directive 90\/496\/EEC, Commission Directive 1999\/10\/EC, Directive 2000\/13\/EC of the European Parliament and of the Council, Commission Directives 2002\/67\/EC and 2008\/5\/EC and Commission Regulation (EC) No 608\/2004. 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