{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T22:40:10Z","timestamp":1781908810738,"version":"3.54.5"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"16","license":[{"start":{"date-parts":[[2016,5,30]],"date-time":"2016-05-30T00:00:00Z","timestamp":1464566400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1368980016001294_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>We evaluated the effect of home fortification with multiple micronutrient powder (MNP) on anaemia and micronutrient status of young Amazonian children.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980016001294_abs2\" sec-type=\"general\"><jats:title>Design<\/jats:title><jats:p>A pragmatic controlled trial was performed. A control group (CG) of children aged 11\u201314 months was recruited in the routine of primary health-care centres for assessing anaemia and micronutrient status. At the same time, an intervention group (IG) of infants aged 6\u20138 months was recruited in the same health centres to receive MNP daily in complementary feeding for 2 months. The IG children were assessed 4\u20136 months after enrolment (<jats:italic>n<\/jats:italic>112) when they had reached the age of the CG participants (<jats:italic>n<\/jats:italic>128) for comparisons.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980016001294_abs3\" sec-type=\"general\"><jats:title>Setting<\/jats:title><jats:p>Primary health centres in Rio Branco city, Brazilian Amazon.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980016001294_abs4\" sec-type=\"subjects\"><jats:title>Subjects<\/jats:title><jats:p>A total of 240 children aged&lt;2 years.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980016001294_abs5\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>In the CG, the prevalence of anaemia (Hb&lt;110 g\/l), iron deficiency (ID; plasma ferritin &lt;12 \u03bcg\/l or soluble transferrin receptor &gt;8\u00b73 mg\/l) and vitamin A deficiency (VAD; serum retinol &lt;0\u00b770 \u03bcmol\/l) was 20\u00b73 %, 72\u00b74 % and 18\u00b76 %, respectively. Among the IG participants (aged 11\u201314 months), the prevalence of anaemia, ID and VAD was 15\u00b72 %, 25\u00b72 % and 4\u00b77 %, respectively. The IG had a lower likelihood of ID (prevalence ratio (95 % CI): 0\u00b734 (0\u00b724, 0\u00b749)) and VAD (0\u00b725 (0\u00b709, 0\u00b764)).<\/jats:p><\/jats:sec><jats:sec id=\"S1368980016001294_abs6\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Home fortification of complementary feeding delivered through primary health care was effective in reducing iron and vitamin A deficiencies among young Amazonian children.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1368980016001294","type":"journal-article","created":{"date-parts":[[2016,5,30]],"date-time":"2016-05-30T05:20:16Z","timestamp":1464585616000},"page":"3039-3047","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":13,"title":["Multiple micronutrients in powder delivered through primary health care reduce iron and vitamin A deficiencies in young Amazonian children"],"prefix":"10.1017","volume":"19","author":[{"given":"Cristieli SM","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia","family":"Sampaio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascoal T","family":"Muniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marly A","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the ENFAC Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,5,30]]},"reference":[{"key":"S1368980016001294_ref31","doi-asserted-by":"publisher","DOI":"10.1177\/156482650402500401"},{"key":"S1368980016001294_ref11","volume-title":"Use of Multiple Micronutrient Powders for Home Fortification of Foods Consumed by Infants and Children 6\u201323 Months of Age","year":"2011"},{"key":"S1368980016001294_ref10","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2011000200012"},{"key":"S1368980016001294_ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.11.003"},{"key":"S1368980016001294_ref1","volume-title":"Iron Deficiency Anaemia Assessment, Prevention and Control. A Guide for Programme Managers","year":"2001"},{"key":"S1368980016001294_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70001-9"},{"key":"S1368980016001294_ref5","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-2-67"},{"key":"S1368980016001294_ref6","doi-asserted-by":"publisher","DOI":"10.3945\/jn.112.169524"},{"key":"S1368980016001294_ref14","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1471-2458-13-S3-S22","article-title":"Effectiveness of micronutrient powders (MNP) in women and children","volume":"13","author":"Salam","year":"2013","journal-title":"BMC Public Health"},{"key":"S1368980016001294_ref22","volume-title":"A Procedure to Estimate Accuracy and Reliability of HemoCue Measurements of Survey Workers","author":"Burger","year":"2003"},{"key":"S1368980016001294_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60437-7"},{"key":"S1368980016001294_ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151097"},{"key":"S1368980016001294_ref19","volume-title":"Designing Clinical Research","author":"Hulley","year":"2001"},{"key":"S1368980016001294_ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980012003047"},{"key":"S1368980016001294_ref29","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2013.67"},{"key":"S1368980016001294_ref20","volume-title":"Physical Status: The Use and Interpretation of Anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series","year":"1995"},{"key":"S1368980016001294_ref35","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-10-129"},{"key":"S1368980016001294_ref4","volume-title":"Worldwide Prevalence of Anaemia 1993\u20132005. WHO Global Database on Anaemia","year":"2008"},{"key":"S1368980016001294_ref18","unstructured":"Minist\u00e9rio da Sa\u00fade, Departamento de Aten\u00e7\u00e3o B\u00e1sica (2014) Portal da Sa\u00fade. Hist\u00f3rico de Cobertura da Sa\u00fade da Fam\u00edlia. Equipes da Sa\u00fade da Fam\u00edlia. Fonte: MS\/SAS\/DAB e IBGE. http:\/\/dab.saude.gov.br\/dab\/historico_cobertura_sf\/historico_cobertura_sf_relatorio.php (accessed May 2014)."},{"key":"S1368980016001294_ref38","doi-asserted-by":"publisher","DOI":"10.1177\/15648265100312S210"},{"key":"S1368980016001294_ref30","first-page":"1","article-title":"Vitamin A policies need rethinking","volume":"10","author":"Mason","year":"2014","journal-title":"Int J Epidemiol"},{"key":"S1368980016001294_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60891-6"},{"key":"S1368980016001294_ref17","unstructured":"Instituto Brasileiro de Geografia e Estat\u00edstica (2010) Cidades. Resultados da amostra do Censo Demogr\u00e1fico 2010. http:\/\/cidades.ibge.gov.br\/xtras\/perfil.php?codmun=120040 (accessed May 2014)."},{"key":"S1368980016001294_ref3","volume-title":"Global Prevalence of Vitamin A Deficiency in Populations at Risk 1995\u20132005. WHO Global Database on Vitamin A Deficiency","year":"2009"},{"key":"S1368980016001294_ref7","doi-asserted-by":"publisher","DOI":"10.1159\/000371618"},{"key":"S1368980016001294_ref27","first-page":"85","article-title":"Antenatal care differences in Brazilian urban and rural areas: a cross-sectional population-based study","volume":"17","author":"Cardoso","year":"2013","journal-title":"Rev Min Enferm"},{"key":"S1368980016001294_ref36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2011.00357.x"},{"key":"S1368980016001294_ref33","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60880-1"},{"key":"S1368980016001294_ref13","doi-asserted-by":"publisher","DOI":"10.3945\/jn.107.086199"},{"key":"S1368980016001294_ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2009.00190.x"},{"key":"S1368980016001294_ref8","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2013001300014"},{"key":"S1368980016001294_ref28","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.111.030072"},{"key":"S1368980016001294_ref12","first-page":"CD008959","article-title":"Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age","volume":"9","author":"De-Regil","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"S1368980016001294_ref25","doi-asserted-by":"publisher","DOI":"10.1089\/152308604322899305"},{"key":"S1368980016001294_ref21","first-page":"S76","article-title":"WHO child growth standards based on length\/height, weight and age","volume":"450","year":"2006","journal-title":"Acta Paediatr Suppl"},{"key":"S1368980016001294_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61731-1"},{"key":"S1368980016001294_ref26","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-015-0635-z"},{"key":"S1368980016001294_ref23","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2010.29284"},{"key":"S1368980016001294_ref24","doi-asserted-by":"publisher","DOI":"10.1177\/15648265080292S129"}],"container-title":["Public Health Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1368980016001294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T05:23:40Z","timestamp":1600665820000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1368980016001294\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,30]]},"references-count":39,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S1368980016001294"],"URL":"https:\/\/doi.org\/10.1017\/s1368980016001294","relation":{},"ISSN":["1368-9800","1475-2727"],"issn-type":[{"value":"1368-9800","type":"print"},{"value":"1475-2727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,30]]},"assertion":[{"value":"Copyright \u00a9 The Authors 2016\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}