{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:46:37Z","timestamp":1786999597438,"version":"build-2736575974"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T00:00:00Z","timestamp":1588204800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1368980019005123_as1\" sec-type=\"other\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To estimate the current evidence regarding the association between gestational acrylamide (AA) exposure and offspring\u2019s growth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980019005123_as2\" sec-type=\"other\">\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980019005123_as3\" sec-type=\"other\">\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>A systematic literature search for relevant publications was conducted using PubMed, Medline, Embase, Web of Science databases from inception to 26 April 2019. The standardised mean difference (SMD) or OR with 95 % CI was selected as the effect sizes and was calculated using a random effects model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980019005123_as4\" sec-type=\"other\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Five cohort studies including 54\u00a0728 participants were identified. Offspring\u2019s birth weight was significantly lower in high AA exposure group than in low AA exposure group (SMD \u20130\u00b705, 95 % CI \u20130\u00b709, \u20130\u00b702,\n                      <jats:italic>P<\/jats:italic>\n                      = 0\u00b7005). There was also an association between maternal AA exposure and small for gestational age (OR 1\u00b714, 95 % CI 1\u00b706, 1\u00b723,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0\u00b7001). In addition, pooled ORs suggested that children had a high risk of developing overweight\/obesity in the future in maternal high AA exposure group (OR 1\u00b714, 95 % CI 1\u00b708, 1\u00b721,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0\u00b7001 at age 3; OR 1\u00b713, 95 % CI 1\u00b707, 1\u00b719,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0\u00b7001 at age 5; OR 1\u00b709, 95 % CI 1\u00b702, 1\u00b716,\n                      <jats:italic>P<\/jats:italic>\n                      = 0\u00b7020 at age 8).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980019005123_as5\" sec-type=\"other\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>These findings have important implications for conducting health education, providing guidance on maternal diet and developing an appropriate dietary strategy for pregnant women to reduce dietary AA exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1368980019005123","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T04:39:17Z","timestamp":1588221557000},"page":"1791-1799","source":"Crossref","is-referenced-by-count":15,"title":["Relationship between gestational acrylamide exposure and offspring\u2019s growth: a systematic review and meta-analysis of cohort studies"],"prefix":"10.1017","volume":"23","author":[{"given":"Yongle","family":"Zhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianjia","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2443-911X","authenticated-orcid":false,"given":"Yu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2020,4,30]]},"reference":[{"key":"S1368980019005123_ref32","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqy353"},{"key":"S1368980019005123_ref31","doi-asserted-by":"publisher","DOI":"10.1038\/s41430-018-0316-6"},{"key":"S1368980019005123_ref29","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1446"},{"key":"S1368980019005123_ref27","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0901021"},{"key":"S1368980019005123_ref26","doi-asserted-by":"publisher","DOI":"10.1265\/jjh.69.166"},{"key":"S1368980019005123_ref25","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0309"},{"key":"S1368980019005123_ref23","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26647"},{"key":"S1368980019005123_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ando.2017.04.009"},{"key":"S1368980019005123_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2009.11.049"},{"key":"S1368980019005123_ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"S1368980019005123_ref18","unstructured":"18. 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(2011) The Newcastle\u2013Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in Meta-Analyses. www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp (accessed November 2012)."},{"key":"S1368980019005123_ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyq267"},{"key":"S1368980019005123_ref13","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.008870"},{"key":"S1368980019005123_ref12","first-page":"1","article-title":"Maternal acrylamide intake during pregnancy and sex hormone levels in maternal and umbilical cord blood and birth size of offspring","volume":"14","author":"Nagata","year":"2018","journal-title":"Nutr Cancer"},{"key":"S1368980019005123_ref11","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1205327"},{"key":"S1368980019005123_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2018.01.004"},{"key":"S1368980019005123_ref8","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1205396"},{"key":"S1368980019005123_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2017.03.016"},{"key":"S1368980019005123_ref4","first-page":"4104","article-title":"Scientific opinion on acrylamide in food","volume":"13","year":"2015","journal-title":"EFSA J"},{"key":"S1368980019005123_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2012.04.004"},{"key":"S1368980019005123_ref1","first-page":"1","article-title":"IARC working group on the evaluation of carcinogenic risks to humans: some industrial chemicals. 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