{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T17:27:44Z","timestamp":1785432464849,"version":"3.56.0"},"reference-count":50,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1368980025101602_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the nutritional status of adults with beta thalassemia major in Vietnam by analysing body composition parameters and assessing the adequacy of energy, macronutrient and micronutrient intake.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980025101602_as2\">\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted among adult patients with beta thalassemia major. Nutritional status was assessed using three components: BMI, body composition and dietary intake.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980025101602_as3\">\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Department of Thalassemia, The National Institute of Hematology and Blood Transfusion in Vietnam.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980025101602_as4\">\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>317 adult patients with beta thalassemia major (54\u00b72 % females, median age 32).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980025101602_as5\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Nearly half (49\u00b75 %) of the patients had a normal BMI, while 18\u00b73 % were severely underweight and 32\u00b72 % were underweight. Severe underweight patients exhibited lower body fat, bone mineral content and visceral fat. Average daily energy intake (1449\u00b79 kcal) was significantly below the estimated requirement (2079\u00b75 kcal), with 81\u00b74 % of patients consuming less than 85 % of their energy needs. Severely underweight patients consumed 12\u00b706 g\/d less fat (95 % CI: 6\u00b785, 17\u00b726) and 10\u00b742 g\/d less protein (95 % CI: 4\u00b742, 16\u00b742) than normal weight patients. Severe deficiencies in Ca, Mg, Fe and B-complex vitamins were prevalent, with the lowest mean probability of adequacy for minerals and vitamins observed in severely underweight patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1368980025101602_as6\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study provides the first comprehensive assessment of the nutritional status of beta thalassemia major patients in Vietnam, revealing critical gaps in energy and nutrient intake. Evidence-based strategies, including dietary education and interventions tailored to the unique needs of this population, are urgently needed to improve nutritional outcomes and overall health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1368980025101602","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T10:47:09Z","timestamp":1766746029000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Nutritional deficiencies among adults with beta thalassemia major in Vietnam"],"prefix":"10.1017","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5675-9396","authenticated-orcid":false,"given":"Thi Ngoc Anh","family":"Hoang","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03anxx281","id-type":"ROR","asserted-by":"publisher"}],"name":"PHENIKAA University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ha Linh","family":"Quach","sequence":"additional","affiliation":[{"name":"The University of Sydney"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duc Binh","family":"Vu","sequence":"additional","affiliation":[{"name":"National Institute of Hematology and Blood Transfusion"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thi Thu Ha","family":"Nguyen","sequence":"additional","affiliation":[{"name":"National Institute of Hematology and Blood Transfusion"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khanh Linh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Hospital of Post and Telecommunications"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thi Thu Trang","family":"Dinh","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03anxx281","id-type":"ROR","asserted-by":"publisher"}],"name":"PHENIKAA University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thi Mai An","family":"Bui","sequence":"additional","affiliation":[{"name":"PHENIKAA University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"S1368980025101602_ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.yclnex.2018.04.001"},{"key":"S1368980025101602_ref39","doi-asserted-by":"publisher","DOI":"10.4162\/nrp.2022.16.5.658"},{"key":"S1368980025101602_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21416"},{"key":"S1368980025101602_ref9","doi-asserted-by":"publisher","DOI":"10.31031\/NTNF.2020.05.000607"},{"key":"S1368980025101602_ref24","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2020.581043"},{"key":"S1368980025101602_ref43","doi-asserted-by":"publisher","DOI":"10.3390\/nu16213637"},{"key":"S1368980025101602_ref48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2008.00778.x"},{"key":"S1368980025101602_ref11","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2023.026"},{"key":"S1368980025101602_ref23","unstructured":"23. 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