{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T07:50:18Z","timestamp":1744357818529},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T00:00:00Z","timestamp":1494201600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J Radiother Pract"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1460396917000024_abs1\" sec-type=\"general\"><jats:title>Background<\/jats:title><jats:p>Accupuncture-like transcutaneous electrical nerve stimulation (ALTENS) therapy has been shown in prospective studies to be effective in the treatment of radiation-induced xerostomia. Those studies treated patients within 27 months from end of radiation with ALTENS delivered in the clinic using a Codetron unit. However, that unit is no longer produced and there is limited data on success of ALTENS when delivered at home.<\/jats:p><\/jats:sec><jats:sec id=\"S1460396917000024_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A 50-year old man with xerostomia, 8 years post-radiation for T4N1 squamous cell carcinoma of the tonsillar fossa, was given ALTENS with a currently commercially available unit from Girish Surgical. He used the unit at home, 20 minutes daily for 8 weeks.<\/jats:p><\/jats:sec><jats:sec id=\"S1460396917000024_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>After 8 weeks of ALTENS therapy the patient saw a reduction in the Self-Reported University of Michigan Xerostomia-Related Quality of Life Scale from 20 to 1.<\/jats:p><\/jats:sec><jats:sec id=\"S1460396917000024_abs4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>This case report demonstrates (1) the Girish Surgical unit is effective, (2) self-administration of ALTENS in patients who cannot come to clinic regularly may be practical and (3) ALTENS can still offer durable benefit to patients even 8 years after chemoradiation therapy.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1460396917000024","type":"journal-article","created":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T01:30:48Z","timestamp":1494207048000},"page":"217-220","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Accupuncture-like transcutaneous electrical nerve stimulation therapy success using a commercially available unit 8 years post-radiation for xerostomia: a case report"],"prefix":"10.1017","volume":"16","author":[{"given":"Austin J.","family":"Iovoli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anurag K.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,5,8]]},"reference":[{"key":"S1460396917000024_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-016-1255-0"},{"key":"S1460396917000024_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(03)00572-8"},{"key":"S1460396917000024_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20456"},{"key":"S1460396917000024_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2015.01.050"},{"key":"S1460396917000024_ref1","first-page":"7","article-title":"Xerostomia: diagnosis and management","volume":"10","author":"Greenspan","year":"1996","journal-title":"Oncology (Williston Park)"},{"key":"S1460396917000024_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(00)00063-4"},{"key":"S1460396917000024_ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S1460396915000576"},{"key":"S1460396917000024_ref2","first-page":"252","article-title":"Effect of pilocarpine during radiation therapy: results of RTOG 97-09, a phase III randomized study in head and neck cancer patients","volume":"4","author":"Scarantino","year":"2006","journal-title":"J Support Oncol"},{"key":"S1460396917000024_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27382"}],"container-title":["Journal of Radiotherapy in Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1460396917000024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T22:04:21Z","timestamp":1555538661000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1460396917000024\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,8]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S1460396917000024"],"URL":"https:\/\/doi.org\/10.1017\/s1460396917000024","relation":{},"ISSN":["1460-3969","1467-1131"],"issn-type":[{"value":"1460-3969","type":"print"},{"value":"1467-1131","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,8]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2017\u00a0This is an Open Access article, distributed\nunder the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}