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These data indicate that compromised synaptic plasticity in prefrontal to accumbens projections is a common feature of at least two distinct classes of addictive drug.<\/jats:p>","DOI":"10.1017\/s1461145712001071","type":"journal-article","created":{"date-parts":[[2012,10,31]],"date-time":"2012-10-31T11:43:20Z","timestamp":1351683800000},"page":"1165-1167","source":"Crossref","is-referenced-by-count":58,"title":["Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration"],"prefix":"10.1093","volume":"16","author":[{"given":"Haowei","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"Kalivas","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Medical University of South Carolina, Charleston, SC, 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