{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T22:22:46Z","timestamp":1775427766628,"version":"3.50.1"},"reference-count":47,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"unspecified","delay-in-days":61,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Prim Health Care Res Dev"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:sec id=\"S1463423625000192_as1\">\n\t    <jats:title>Background:<\/jats:title>\n\t    <jats:p>Cardiovascular disease (CVD) poses a substantial global health burden, necessitating effective and scalable interventions for primary prevention. Despite the increasing recognition of peer-based interventions in managing chronic diseases, their application in CVD prevention still needs to be explored.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1463423625000192_as2\">\n\t    <jats:title>Aims:<\/jats:title>\n\t    <jats:p>We describe the protocol of a quasi-experiment to evaluate the effectiveness of a peer-led digital health lifestyle intervention, MYCardio-PEER, for a low-income community at risk for CVD. This study aims to assess the effectiveness of MYCardio-PEER in improving the participants\u2019 knowledge, lifestyle behaviours and biomarkers related to CVD. Secondarily, we aim to assess the adherence and satisfaction of participants towards MYCardio-PEER.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1463423625000192_as3\">\n\t    <jats:title>Methods:<\/jats:title>\n\t    <jats:p>A minimum total sample of 68 low-income community members at risk for CVD will be recruited and allocated either to the control group or the intervention group. Participants in the control group will receive standard lifestyle advice and printed materials for CVD prevention, while the intervention group will participate in the 8-week MYCardio-PEER intervention program. The participants will be assessed at Week 0 (baseline), Week 8 (post-intervention) and Week 20 (post-follow-up).<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1463423625000192_as4\">\n\t    <jats:title>Discussion:<\/jats:title>\n\t    <jats:p>We anticipate a net improvement in CVD risk score, besides investigating the effectiveness of the intervention program on CVD-related knowledge, biomarkers, and diet and lifestyle behaviours. The successful outcome of this study is essential for various healthcare professionals and stakeholders to implement population-based, cost-effective, and accessible interventions in reducing CVD prevalence in the country.<\/jats:p>\n\t    <jats:p><jats:bold>Trial registration<\/jats:bold>: ClinicalTrials.gov (NCT06408493)<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/s1463423625000192","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T06:45:31Z","timestamp":1740984331000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Peer-led digital health lifestyle intervention for a low-income community at risk for cardiovascular diseases (MYCardio-PEER): a quasi-experimental study protocol"],"prefix":"10.1017","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3509-7546","authenticated-orcid":false,"given":"Geok Pei","family":"Lim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1087-0128","authenticated-orcid":false,"given":"Jamuna Rani","family":"Appalasamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0063-1761","authenticated-orcid":false,"given":"Badariah","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5415-2163","authenticated-orcid":false,"given":"Kia Fatt","family":"Quek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3658-3709","authenticated-orcid":false,"given":"Shazwani","family":"Shaharuddin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8238-9659","authenticated-orcid":false,"given":"Amutha","family":"Ramadas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"S1463423625000192_ref28","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17082641"},{"key":"S1463423625000192_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s41347-019-00105-x"},{"key":"S1463423625000192_ref32","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare8010026"},{"key":"S1463423625000192_ref39","doi-asserted-by":"publisher","DOI":"10.1097\/NUR.0b013e3181a42373"},{"key":"S1463423625000192_ref20","doi-asserted-by":"publisher","DOI":"10.3945\/an.117.016980"},{"key":"S1463423625000192_ref26","doi-asserted-by":"publisher","DOI":"10.1080\/08964289.2015.1034645"},{"key":"S1463423625000192_ref22","volume-title":"Nutritional Epidemiology: Dietary Assessments: Use, Design Concepts, Biologica Markers, Pitfalls and Validation","author":"Johansson","year":"2014"},{"key":"S1463423625000192_ref47","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-023-00764-4"},{"key":"S1463423625000192_ref29","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-022-13811-8"},{"key":"S1463423625000192_ref13","volume-title":"The Key Findings: Income, Poverty, Inequality, Expenditure, Basic Amenities","year":"2020"},{"key":"S1463423625000192_ref9","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"S1463423625000192_ref16","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.41.4.1149"},{"key":"S1463423625000192_ref27","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-18328-w"},{"key":"S1463423625000192_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32007-0"},{"key":"S1463423625000192_ref36","volume-title":"Train peer supporters","year":"2021"},{"key":"S1463423625000192_ref5","unstructured":"Centers for Disease Control and Prevention (CDC) (2021) Know your risk for heart disease. 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