{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T05:31:55Z","timestamp":1786426315395,"version":"build-2736575974"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"unspecified","delay-in-days":222,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Prim Health Care Res Dev"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1463423626101625_as1\">\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aimed to determine the effect of a single-session music intervention on pain intensity, state anxiety, and vital signs in cancer patients receiving palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1463423626101625_as2\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>While music therapy is recognized as a non-pharmacological complementary tool, its simultaneous effect on both physiological and psychological parameters requires robust methodological evaluation within specific palliative care settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1463423626101625_as3\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cluster quasi-experimental pre-test\/post-test control group design was conducted across two palliative care centres. The sample comprised 32 patients (Intervention: 16, Control: 16). To prevent treatment contamination, allocation was systematically performed at the room level rather than the individual level. The intervention group received a 30-minute session of instrumental Turkish classical music (Hicaz and Buselik maqams) via headphones, while the control group rested in bed. Data were collected using a Patient Description Form, Visual Analog Scale (VAS), State\u2013Trait Anxiety Inventory (STAI), and a Physiological Parameter Monitoring Form. Linear Mixed Models (LMM) analyzed group \u00d7 time interactions to account for clustering effects and baseline socio-demographic imbalances.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1463423626101625_as4\">\n                    <jats:title>Findings:<\/jats:title>\n                    <jats:p>\n                      Analysis revealed significant group \u00d7 time interactions Post-intervention, the intervention group showed statistically significant reduction in pain intensity and state anxiety scores compared to the control group (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05). Vital signs (pulse rate, respiratory rate, and blood pressure) demonstrated significant stabilization, alongside a significant increase in oxygen saturation (SpO\n                      <jats:sub>2<\/jats:sub>\n                      ) in the intervention group. A 30-minute maqam-based instrumental music session shows\u00a0potential as a stabilizing, non-pharmacological adjunct for acute symptom management in palliative cancer patients. Due to the small sample size and cluster-allocation, findings provide preliminary evidence.\n                    <\/jats:p>\n                    <jats:sec id=\"S1463423626101625_as5\">\n                      <jats:title>Clinical trial number:<\/jats:title>\n                      <jats:p>NCT07262151 (ClinicalTrials.gov). Retrospectively registered 3 December 2025.<\/jats:p>\n                    <\/jats:sec>\n                  <\/jats:sec>","DOI":"10.1017\/s1463423626101625","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T05:23:39Z","timestamp":1786425819000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["The determination of the effect of music on pain, anxiety, and vital findings in cancer patients treated in palliative care centres: a cluster quasi-experimental study"],"prefix":"10.1017","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7221-0814","authenticated-orcid":false,"given":"G\u00fcls\u00fcm","family":"Kehribar","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/037vvf096","id-type":"ROR","asserted-by":"publisher"}],"name":"Karamano\u011flu Mehmetbey University Vocational School of Health Services"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9977-158X","authenticated-orcid":false,"given":"P\u0131nar","family":"Tekinsoy Kart\u0131n","sequence":"additional","affiliation":[{"name":"Erciyes University Faculty of Health Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"S1463423626101625_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2020.01.002"},{"key":"S1463423626101625_ref7","first-page":"1","article-title":"Implementation and outcomes of complementary therapies in hospice care: An integrative review","volume":"15","author":"Dingley","year":"2021","journal-title":"Journal of Palliative Care and Social Practice"},{"key":"S1463423626101625_ref16","volume-title":"State-Trait Anxiety Inventory Handbook","author":"\u00d6ner","year":"1983"},{"key":"S1463423626101625_ref22","first-page":"61","article-title":"An evaluation of palliative care service effect in patients with cancer diagnosis: Comparison in terms of the symptom level and care satisfaction","volume":"32","author":"Sayg\u0131l\u0131","year":"2020","journal-title":"A\u011fr\u0131 - The Journal of The Turkish Society of Algology"},{"key":"S1463423626101625_ref9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.00013"},{"key":"S1463423626101625_ref23","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-021-00514-z"},{"key":"S1463423626101625_ref24","volume-title":"STAI, Manual for the State-trait Anxiety Inventory","author":"Spielberger","year":"1970"},{"key":"S1463423626101625_ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.00651"},{"key":"S1463423626101625_ref25","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"S1463423626101625_ref17","doi-asserted-by":"publisher","DOI":"10.26567\/JOHSE.2018142106"},{"key":"S1463423626101625_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s10943-018-0701-4"},{"key":"S1463423626101625_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.12790"},{"key":"S1463423626101625_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2010.03.008"},{"key":"S1463423626101625_ref13","doi-asserted-by":"publisher","DOI":"10.4236\/health.2018.102015"},{"key":"S1463423626101625_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(83)90126-4"},{"key":"S1463423626101625_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctcp.2021.101416"},{"key":"S1463423626101625_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-014-2478-7"},{"key":"S1463423626101625_ref2","first-page":"002","article-title":"Effects of music therapy on vital signs and anxiety: A study with terminally ill patients","volume":"1","author":"Antoniazza","year":"2018","journal-title":"Journal of Hospice and Palliative Medical Care"},{"key":"S1463423626101625_ref27","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-022-06233-9"},{"key":"S1463423626101625_ref20","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.14205"},{"key":"S1463423626101625_ref21","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14184416"},{"key":"S1463423626101625_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4470"},{"key":"S1463423626101625_ref6","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16183130"},{"key":"S1463423626101625_ref8","doi-asserted-by":"publisher","DOI":"10.1177\/00302228211059891"},{"key":"S1463423626101625_ref10","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.00470"},{"key":"S1463423626101625_ref14","first-page":"149","article-title":"Symptom distress: Implementation of palliative care guidelines to improve pain, fatigue, and anxiety in patients with advanced cancer","volume":"23","author":"Koesel","year":"2019","journal-title":"Clinical Journal of Oncology Nursing"}],"container-title":["Primary Health Care Research &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1463423626101625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T05:23:44Z","timestamp":1786425824000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1463423626101625\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":26,"alternative-id":["S1463423626101625"],"URL":"https:\/\/doi.org\/10.1017\/s1463423626101625","relation":{},"ISSN":["1463-4236","1477-1128"],"issn-type":[{"value":"1463-4236","type":"print"},{"value":"1477-1128","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e91"}}