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Rev."],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Mycoplasma bovis<\/jats:italic>\n                    is an important and emerging cause of respiratory disease and arthritis in feedlot cattle and young dairy and veal calves, and has a variety of other disease manifestations in cattle.\n                    <jats:italic>M. bovis<\/jats:italic>\n                    is certainly capable of causing acute respiratory disease in cattle, yet the attributable fraction has been difficult to estimate. In contrast,\n                    <jats:italic>M. bovis<\/jats:italic>\n                    is more accepted as a cause of chronic bronchopneumonia with caseous and perhaps coagulative necrosis, characterized by persistent infection that seems poorly responsive to many antibiotics. An understanding of the disease has been recently advanced by comparisons of natural and experimentally induced disease, development of molecular diagnostic tools, and understanding some aspects of virulence, yet uncertainties regarding protective immunity, the importance of genotypic diversity, mechanisms of virulence, and the role of co-pathogens have restricted our understanding of pathogenesis and our ability to effectively control the disease. This review critically considers the relationship between\n                    <jats:italic>M. bovis<\/jats:italic>\n                    infection and the various manifestations of the bovine respiratory disease complex, and addresses the pathogenesis, clinical and pathologic sequelae, laboratory diagnosis and control of disease resulting from\n                    <jats:italic>M. bovis<\/jats:italic>\n                    infection in the bovine respiratory tract.\n                  <\/jats:p>","DOI":"10.1017\/s1466252307001351","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T08:43:31Z","timestamp":1201164211000},"page":"161-186","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":162,"title":["<i>Mycoplasma bovis<\/i>\n                    pneumonia in cattle"],"prefix":"10.1017","volume":"8","author":[{"given":"Jeff L.","family":"Caswell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Archambault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2008,1,24]]},"reference":[{"key":"S1466252307001351_ref042","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0450.2005.00845.x"},{"key":"S1466252307001351_ref041","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcp.2004.11.007"},{"key":"S1466252307001351_ref044","doi-asserted-by":"publisher","DOI":"10.1177\/104063870601800105"},{"key":"S1466252307001351_ref040","doi-asserted-by":"publisher","DOI":"10.1023\/B:VERC.0000045953.39260.68"},{"key":"S1466252307001351_ref030","doi-asserted-by":"publisher","DOI":"10.1136\/vr.142.19.516"},{"key":"S1466252307001351_ref027","doi-asserted-by":"publisher","DOI":"10.1023\/B:VERC.0000017282.27591.92"},{"key":"S1466252307001351_ref022","first-page":"626","article-title":"Detection of Mycoplasma bovis by different PCR systems","volume":"126","author":"B\u00edr\u00f3","year":"2004","journal-title":"Magyar \u00c1llatorvosok Lapja"},{"key":"S1466252307001351_ref018","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-142-9-2463"},{"key":"S1466252307001351_ref016","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1128\/AAC.41.2.269","article-title":"Characterization of Mycoplasma hominis mutations involved in resistance to fluoroquinolones","volume":"41","author":"Bebear","year":"1997","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"S1466252307001351_ref013","doi-asserted-by":"publisher","DOI":"10.1136\/vr.135.22.531"},{"key":"S1466252307001351_ref021","doi-asserted-by":"publisher","DOI":"10.1136\/vr.112.13.294"},{"key":"S1466252307001351_ref009","article-title":"The role of Mycoplasma bovis in bovine respiratory disease outbreaks in veal calf feedlots","author":"Arcangioli","year":"2007","journal-title":"Veterinary Journal"},{"key":"S1466252307001351_ref056","doi-asserted-by":"publisher","DOI":"10.1136\/vr.150.9.268"},{"key":"S1466252307001351_ref007","first-page":"341","article-title":"The microbial flora of the respiratory tract in feedlot calves: associations between nasopharyngeal and bronchoalveolar lavage cultures","volume":"55","author":"Allen","year":"1991","journal-title":"Canadian Journal of Veterinary Research"},{"key":"S1466252307001351_ref103","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1128\/jcm.9.6.709-711.1979","article-title":"Isolation of Mycoplasma bovis from a patient with systemic illness","volume":"9","author":"Madoff","year":"1979","journal-title":"Journal of Clinical Microbiology"},{"key":"S1466252307001351_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2007.01.007"},{"key":"S1466252307001351_ref031","doi-asserted-by":"publisher","DOI":"10.1136\/vr.146.13.368"},{"key":"S1466252307001351_ref106","first-page":"499","article-title":"Mycoplasma infection in calves. 3. 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