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The most common route of infection for people is via ingestion of contaminated ready-to-eat food products such as produce, soft cheeses and deli meats. In the United States,<jats:italic>L. monocytogenes<\/jats:italic>causes relatively few cases of clinical disease compared to other food-borne pathogens. However, clinical listeriosis is associated with high mortality, especially in immunocompromised patients, pregnant women, neonates, and the elderly.<jats:italic>Listeria<\/jats:italic>is an intracellular pathogen, which has been widely used in basic research to elucidate mechanisms of molecular pathogenesis and protective cell-mediated immunity. Despite the sizeable knowledge on<jats:italic>L. monocytogenes<\/jats:italic>pathogenesis, key points regarding listeriosis during pregnancy and the perinatal period remain unknown. This review summarizes listeriosis in humans and domestic animals during pregnancy, and animal models used to study the pathogenesis and immune response to<jats:italic>L. monocytogenes<\/jats:italic>infection during these periods.<\/jats:p>","DOI":"10.1017\/s1466252312000242","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T13:18:54Z","timestamp":1359119934000},"page":"30-39","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":38,"title":["Pathogenesis of listeriosis during pregnancy"],"prefix":"10.1017","volume":"14","author":[{"given":"Keith P.","family":"Poulsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles 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