{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T21:50:29Z","timestamp":1723153829058},"reference-count":28,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T00:00:00Z","timestamp":1471478400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Anim. Health. Res. Rev."],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The tetracyclines (TTC) and sulfonamides are among the most common residues found in bulk raw milk samples. Detection of drug residues in bulk milk (BM) tankers demonstrates that the product is not suitable for human consumption. Discarding BM with residue-contaminated milk is a waste of a valuable commodity, and a repurposing for consumption at calf ranches is a way to recapture some value. However, if calves consuming milk with drug residues are slaughtered for veal, their meat could contain drug residues. The objective of this review is to provide a residue avoidance strategy for TTC and sulfonamide residues in veal. To determine the pharmacokinetic properties of each drug a structured review of the literature was performed and the study inclusion criteria were that the publication used dairy breed calves, with body weight &lt;330 kg or &lt;6 months of age. The most pertinent parameters were determined to be plasma, tissue elimination half-lives, and systemic bioavailability. The results of this review were integrated with milk and tissue testing levels of quantification and tissue tolerances to formulate a recommended withdrawal interval for calves ingesting this milk. The suggested withdrawal interval of 20 days will ensure that no veal calves will test positive for residues from being fed this milk.<\/jats:p>","DOI":"10.1017\/s1466252316000098","type":"journal-article","created":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T11:07:03Z","timestamp":1471518423000},"page":"127-136","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Protocol for diversion of confirmed positive bulk raw milk tankers to calf ranches \u2013 A review of the Pharmacokinetics of tetracyclines and sulfonamides in veal calves"],"prefix":"10.1017","volume":"17","author":[{"given":"K. D.","family":"DeDonder","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Gehring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. A.","family":"Tell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. E.","family":"Riviere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,8,18]]},"reference":[{"key":"S1466252316000098_ref13","first-page":"882","article-title":"The advantages of a timed-release sulfamethazine bolette for calves","volume":"81","author":"Murphy","year":"1986","journal-title":"Veterinary Medicine"},{"key":"S1466252316000098_ref25","unstructured":"United States Department of Agriculture & Food Safety and Inspection Service (2012). New Analytic methods and Sampling Procedure for the United States National Residue Program for Meat, Poultry, and Egg Products."},{"key":"S1466252316000098_ref11","first-page":"22","article-title":"The effect of citric acid on the availability of tetracyclines in calves","volume":"37","author":"Luthman","year":"1985","journal-title":"Nordisk Veterinaer Medicin"},{"key":"S1466252316000098_ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2885.1982.tb00442.x"},{"key":"S1466252316000098_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/9780470959916"},{"key":"S1466252316000098_ref26","unstructured":"United States Food and Drug Administration (2012). Beta Lactam and Other Test Methods for Use Under Appendix N and Section 6 of The Grade \u2018A\u2019 Pasteurized Milk Ordinance (PMO). M-a-85 (Revision #14) ed. College Park, MD."},{"key":"S1466252316000098_ref15","first-page":"68","article-title":"Absorption in calves of amoxicillin, ampicillin, and oxytetracycline given in milk replacer, water, or an oral rehydration formulation","volume":"44","author":"Palmer","year":"1983","journal-title":"American Journal of Veterinary Research"},{"key":"S1466252316000098_ref19","first-page":"348","article-title":"Concentration of chlortetracycline in the body of dairy calves receiving nutritional levels of the antibiotic","author":"Rusoff","year":"1954","journal-title":"Antibiotics Annual"},{"key":"S1466252316000098_ref24","unstructured":"United States Department of Agriculture & Food and Drug Administration (2012). Tolerances for Residues of New Animal Drugs in Food. 21 CFR 556."},{"key":"S1466252316000098_ref21","unstructured":"Sepp S (1986). Untersuchungen zur Pharmakokinetik von Gentamycin, Ampicillin, Erythromycin, Chlortetracyclin und Sulfadimethoxin beim Mastkalb nach subkutaner oder oraler Verabreichun (Pharmacokinetic studies of ampicillin, erythromycin, chlortetracycline, and sulfdimethoxine of veal calves after subcutaneous and oral administration) . Ph.D. Thesis, University of Munich."},{"key":"S1466252316000098_ref23","doi-asserted-by":"crossref","first-page":"816","DOI":"10.2460\/javma.1991.198.05.816","article-title":"Use of the food animal residue avoidance databank","volume":"198","author":"Sundlof","year":"1991","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"S1466252316000098_ref10","first-page":"292","article-title":"The Availability of Tetracyclines in Calves","volume":"35","author":"Luthman","year":"1983","journal-title":"Nordisk Veterinaer Medicin"},{"key":"S1466252316000098_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2885.2006.00707.x"},{"key":"S1466252316000098_ref8","first-page":"1056","article-title":"Ontogenic changes of trimethoprim\/sulfadizaine pharmacokinetics","volume":"119","author":"Lapka","year":"1980","journal-title":"Zentralblatt Pharmazie, Pharmakotherapie und Laboratoriumsdiagnostik"},{"key":"S1466252316000098_ref27","first-page":"768","article-title":"Development of pharmacokinetic models for sulfonamides in food animals: metabolic depletion profile of sulfdiazine in the calf","volume":"43","author":"Woolley","year":"1982","journal-title":"American Journal of Veterinary Research"},{"key":"S1466252316000098_ref1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-53.2.154"},{"key":"S1466252316000098_ref4","first-page":"27","article-title":"Etude pharacocinetique d'une association chloramphenicol chlortetracycline chez le veau","volume":"162","author":"Dumas","year":"1986","journal-title":"Recueil de Medecine Veterinaire de l'Ecole d'Alfort"},{"key":"S1466252316000098_ref6","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-67.3.555"},{"key":"S1466252316000098_ref14","unstructured":"National Milk Drug Residue Data Base (2013). Fiscal Year 2013 Annual Report. GLH, Incorporated."},{"key":"S1466252316000098_ref17","doi-asserted-by":"crossref","first-page":"966","DOI":"10.2460\/javma.1998.213.07.966","article-title":"Primer on estimating withdrawal times after extralabel drug use","volume":"213","author":"Riviere","year":"1998","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"S1466252316000098_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0368-1742(49)80023-3"},{"key":"S1466252316000098_ref20","first-page":"513","article-title":"Detection of residues in calf carcases after feeding chlortetracycline, oxytetracycline, and zinc bacitracin","volume":"54","author":"Schmidt","year":"1974","journal-title":"Fleischwirtsch"},{"key":"S1466252316000098_ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2885.2011.01327.x"},{"key":"S1466252316000098_ref9","first-page":"637","article-title":"Pharmacokinetics of sulfadimidine in normal and diarrheic calves","volume":"6","author":"Lapka","year":"1978","journal-title":"Drug Metabolism and Disposition"},{"key":"S1466252316000098_ref18","first-page":"614","article-title":"Oznaczanie stezenia sulfadwumetoksypirymidyny we krwi cielat (The significance of the sulfadimethoxine concentration in blood of calves)","volume":"XX","author":"Rolinski","year":"1964","journal-title":"Medycyna Weterynaryjna"},{"key":"S1466252316000098_ref22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2885.1987.tb00110.x"},{"key":"S1466252316000098_ref12","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1186\/BF03548602","article-title":"The influence of feeding and oral rehydration on the bioavailability of oxytetracycline in calves","volume":"28","author":"Luthman","year":"1987","journal-title":"Acta Veterinaria Scandinavica"},{"key":"S1466252316000098_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(80)90426-9"}],"container-title":["Animal Health Research Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1466252316000098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T22:32:06Z","timestamp":1718749926000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1466252316000098\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,18]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S1466252316000098"],"URL":"https:\/\/doi.org\/10.1017\/s1466252316000098","relation":{},"ISSN":["1466-2523","1475-2654"],"issn-type":[{"value":"1466-2523","type":"print"},{"value":"1475-2654","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,18]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2016\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}