{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:35:44Z","timestamp":1793831744510,"version":"4.6.1"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2014,4,24]],"date-time":"2014-04-24T00:00:00Z","timestamp":1398297600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1478951514000200_sec1\"><jats:title>Objective:<\/jats:title><jats:p>Palliative sedation is a common treatment in palliative care. The home is a difficult environment for research, and there are few studies about sedation at home. Our aim was to analyze this practice in a home setting.<\/jats:p><\/jats:sec><jats:sec id=\"S1478951514000200_sec2\"><jats:title>Method:<\/jats:title><jats:p>We conducted a retrospective cross-sectional descriptive study in a home cohort during 2011. The inclusion criteria were as follows: 18 years or older and enrolled in the Palliative Home Care Program (PHCP) with advanced cancer. The variables employed were: sex, age, primary tumor location, and place of death. We also registered indication, type, drug and dose, awareness of diagnosis and prognosis, consent, survival, presence or absence of rales, painful mouth, and ulcers in patients sedated at home. We also collected the opinions of family members and professionals about the suffering of sedated patients.<\/jats:p><\/jats:sec><jats:sec id=\"S1478951514000200_sec3\"><jats:title>Results:<\/jats:title><jats:p>A total of 446 patients (56% at home) of the 617 admitted to the PHCP between January and December of 2011 passed away. The typical patient in our population was a 70-year-old man with a lung tumor. Some 35 (14%) home patients required sedation, compared to 93 (49%) at the hospital. The most frequent indication was delirium (70%), with midazolam the most common drug (mean dose, 40 mg). Survival was around three days. Rales were frequent (57%) as well as awareness of diagnosis and prognosis (77 and 71%, respectively). Perception of suffering after sedation was rare among relatives (17%) and professionals (8%). In most cases, the decision was made jointly by professionals and family members.<\/jats:p><\/jats:sec><jats:sec id=\"S1478951514000200_sec4\"><jats:title>Significance of Results:<\/jats:title><jats:p>Our study confirmed the role of palliative sedation as an appropriate therapeutic tool in the home environment.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1478951514000200","type":"journal-article","created":{"date-parts":[[2014,4,24]],"date-time":"2014-04-24T12:38:04Z","timestamp":1398343084000},"page":"619-624","source":"Crossref","is-referenced-by-count":14,"title":["Palliative sedation for cancer patients included in a home care program: A retrospective study"],"prefix":"10.1017","volume":"13","author":[{"given":"Claudio","family":"Calvo-Espinos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estefania","family":"Ruiz de Gaona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Ruiz de Galarreta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Lopez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2014,4,24]]},"reference":[{"key":"S1478951514000200_ref19","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.226"},{"key":"S1478951514000200_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-009-0632-4"},{"key":"S1478951514000200_ref15","unstructured":"Organizaci\u00f3n M\u00e9dica Colegial (OMC) and the Spanish Society of Palliative Care (SECPAL). Palliative sedation guide. Available from http:\/\/www.secpal.com\/b_archivos\/files\/archivo_271.pdf."},{"key":"S1478951514000200_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2004.02.017"},{"key":"S1478951514000200_ref9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/082585970301900108","article-title":"The cultural differences in perceived value of disclosure and cognition: Spain and Canada","volume":"19","author":"Fainsinger","year":"2003","journal-title":"Journal of Palliative Care"},{"key":"S1478951514000200_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2011.06.027"},{"key":"S1478951514000200_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0269216308100772"},{"key":"S1478951514000200_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216309359996"},{"key":"S1478951514000200_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/10673220802576917"},{"key":"S1478951514000200_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2010.07.013"},{"key":"S1478951514000200_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/0885-3924(96)00042-5"},{"key":"S1478951514000200_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2011.09.006"},{"key":"S1478951514000200_ref8","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2006.0139"},{"key":"S1478951514000200_ref3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.41.1223"},{"key":"S1478951514000200_ref21","first-page":"50","article-title":"Symptom prevalence and control during cancer patients' last days of life","volume":"7","author":"Ventafridda","year":"1991","journal-title":"Journal of Palliative Care"},{"key":"S1478951514000200_ref5","doi-asserted-by":"publisher","DOI":"10.1177\/0269216309107024"},{"key":"S1478951514000200_ref2","first-page":"291","article-title":"Continuous deep sedation in home palliative care units: Case studies in the Florence area in 2000 and in 2003\u20132004","volume":"73","author":"Bulli","year":"2007","journal-title":"Minerva Anestesiologica"},{"key":"S1478951514000200_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2007.10.004"},{"key":"S1478951514000200_ref22","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.30.1184"},{"key":"S1478951514000200_ref10","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.3795"},{"key":"S1478951514000200_ref17","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/082585970902500102","article-title":"Palliative sedation at home","volume":"25","author":"Rosengarten","year":"2009","journal-title":"Journal of Palliative Care"},{"key":"S1478951514000200_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2011.01.014"}],"container-title":["Palliative and Supportive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1478951514000200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T00:30:17Z","timestamp":1555806617000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1478951514000200\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,24]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1478951514000200"],"URL":"https:\/\/doi.org\/10.1017\/s1478951514000200","relation":{},"ISSN":["1478-9515","1478-9523"],"issn-type":[{"value":"1478-9515","type":"print"},{"value":"1478-9523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,24]]}}}