{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:31:56Z","timestamp":1792729916017,"version":"4.5.0"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T00:00:00Z","timestamp":1444780800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951515001066_sec_a1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Motor neuron disease (MND) is an incurable progressive illness, characterized by incessant deterioration of neuromuscular function. Timely commencement of advance care planning (ACP) may enable patients to participate in future care choices. The present systematic review aimed to summarize what is known about the prevalence, content, patient\/caregiver benefits, healthcare professional (HCP) awareness\/support, and healthcare outcomes associated with ACP in the MND setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951515001066_sec_a2\">\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>Quantitative and qualitative studies were identified through database searches and eligibility assessed by one author and verified by her coauthor. Data extraction and quality assessments against standardized criteria were completed by the two authors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951515001066_sec_a3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the 422 studies identified, 16 were included. The research methods generally lacked rigor. Advance directive (AD) prevalence varied considerably across studies. Disease progression was the strongest predictor of AD completion. ACP processes may clarify patients' wishes and promote communication. HCP attitudes or lack of awareness may limit ACP processes. Varying patient preferences may make flexible approaches and timing necessary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951515001066_sec_a4\">\n                    <jats:title>Significance of results:<\/jats:title>\n                    <jats:p>Important benefits may be associated with ACP in the context of a motor neuron disease (e.g., feelings of control\/relief and refusal of unwanted treatments). However, further evidence is required to verify findings and identify optimal streamlined approaches (e.g., use of decision aids) consistent with patients' (and caregivers') needs over time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951515001066","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T23:01:20Z","timestamp":1444777280000},"page":"411-432","source":"Crossref","is-referenced-by-count":52,"title":["Advance care planning in motor neuron disease: A systematic review"],"prefix":"10.1017","volume":"14","author":[{"given":"Leigh","family":"Murray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis N.","family":"Butow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,10,14]]},"reference":[{"key":"S1478951515001066_ref15","doi-asserted-by":"publisher","DOI":"10.3109\/17482968.2010.509865"},{"key":"S1478951515001066_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1208"},{"key":"S1478951515001066_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.05.013"},{"key":"S1478951515001066_ref18","doi-asserted-by":"publisher","DOI":"10.1258\/1355819054308576"},{"key":"S1478951515001066_ref12","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.3.428"},{"key":"S1478951515001066_ref3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-9-59"},{"key":"S1478951515001066_ref19","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.1.53"},{"key":"S1478951515001066_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)61577-8"},{"key":"S1478951515001066_ref28","doi-asserted-by":"publisher","DOI":"10.1097\/00006416-200503000-00007"},{"key":"S1478951515001066_ref13","doi-asserted-by":"publisher","DOI":"10.1179\/096992606X146354"},{"key":"S1478951515001066_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(99)00227-0"},{"key":"S1478951515001066_ref32","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01045.x"},{"key":"S1478951515001066_ref2","doi-asserted-by":"publisher","DOI":"10.1136\/jme.2007.022731"},{"key":"S1478951515001066_ref16","volume-title":"Standard quality assessment criteria for evaluating primary research papers from a variety of fields","author":"Kmet","year":"2004"},{"key":"S1478951515001066_ref31","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.78.923.513"},{"key":"S1478951515001066_ref9","first-page":"340","article-title":"The impact of advance care planning on end-of-life care in elderly patients: Randomized controlled trial","author":"Detering","year":"2010","journal-title":"BMJ"},{"key":"S1478951515001066_ref5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.3.500"},{"key":"S1478951515001066_ref25","first-page":"332","article-title":"District nurses\u2019 attitudes toward patient consent: The case of mechanical ventilation on amyotrophic lateral sclerosis patients","volume":"23","author":"Peretti-Watel","year":"2008","journal-title":"Results from a French national survey. 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