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The most frequent diagnosis was gastrointestinal cancer (28.6%), and 38.9% had a functional performance status of ECOG 2. The median DT score was 4.0 (IQR = 2\u20136), with 56% reporting DT scores \u22654. The three most frequent problems \u22654 were sadness (82.6%), feeling weak (81.2%), worry (79.6%), and &lt;4 were feeling weak (57.7%), fatigue (55.6%), and financial security (52.1%). The variables associated with distress according to the multiple logistic regression analysis were problems with housing (OR = 2.661, 95% CI = 1.538\u20134.602), sadness (OR = 2.533, 95% CI = 1.615\u20133.973), transportation (OR = 1.732, 95% CI = 1.157\u20132.591), eating (OR = 1.626, 95% CI = 1.093\u20132.417), nervousness (OR = 1.547, 95% CI = 1.014\u20132.360), and sleep (OR = 1.469, 95% CI = 1.980\u20132.203).<\/jats:p><\/jats:sec><jats:sec id=\"S1478951520001066_sec_a5\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>The principal factors were related to distress levels, housing problems, transportation issues, and emotional problems such as sadness, nervousness, lower functionality, and younger age. Therefore, psychosocial support is of considerable relevance in palliative care. These findings will help clinicians understand the distress of patients with advanced cancer in palliative care in Latin American countries.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1478951520001066","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T07:47:01Z","timestamp":1606117621000},"page":"447-456","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["Associated factors of distress in patients with advanced cancer: A retrospective study"],"prefix":"10.1017","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5768-8761","authenticated-orcid":false,"given":"Leticia","family":"Ascencio-Huertas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Rosa","family":"Allende-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1294-9657","authenticated-orcid":false,"given":"Tania","family":"Pastrana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"S1478951520001066_ref59","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-015-1102-3"},{"key":"S1478951520001066_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2004.04.016"},{"key":"S1478951520001066_ref67","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1939"},{"key":"S1478951520001066_ref10","doi-asserted-by":"publisher","DOI":"10.1177\/1049909113480841"},{"key":"S1478951520001066_ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4418-4"},{"key":"S1478951520001066_ref73","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(02)00497-9"},{"key":"S1478951520001066_ref39","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1604"},{"key":"S1478951520001066_ref28","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2013.0027"},{"key":"S1478951520001066_ref27","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604420"},{"key":"S1478951520001066_ref50","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.07.101"},{"key":"S1478951520001066_ref40","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951515000760"},{"key":"S1478951520001066_ref42","first-page":"67","article-title":"Chronic stress and the measurement of perceived emotional distress in medicine and health psychology","volume":"17","author":"Moscoso","year":"2011","journal-title":"Liberabit"},{"key":"S1478951520001066_ref3","volume-title":"American Cancer Society. 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