{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T04:24:22Z","timestamp":1793679862846,"version":"4.5.1"},"reference-count":42,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"unspecified","delay-in-days":198,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:sec id=\"S1478951525100370_sec1a\">\n\t    <jats:title>Objectives<\/jats:title>\n\t    <jats:p>As cancer incidence and survival rates rise, caregivers responsible for providing diverse support face increased burden and reduced quality of life (QoL). Although research on web-based interventions for this group is expanding, the impact of these interventions on caregiver burden and QoL remains unclear. This study aims to investigate the effects of web-based interventions on the caregiver burden and QoL of caregivers of patients with cancer.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1478951525100370_sec2b\">\n\t    <jats:title>Methods<\/jats:title>\n\t    <jats:p>Searches were conducted in PubMed, Web of Science, Cochrane Library, CINAHL, Embase, and PsycINFO from database inception to 10 June 2024. Two reviewers independently assessed each study and extracted data. The risk-of-bias in the studies was evaluated using Cochrane\u2019s Risk-of-Bias tool for randomized controlled trials. The intervention effects were calculated using R package Meta version 4.0.3, utilizing standardized mean differences (SMD; Hedge\u2019s \u011d) to calculate pooled effect sizes with 95% confidence intervals (CI). Publication bias assessment and sensitivity analysis were conducted to ensure the robustness of the results.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1478951525100370_sec3c\">\n\t    <jats:title>Results<\/jats:title>\n\t    <jats:p>We reviewed 13 randomized controlled trials; our analysis indicated a small effect size of web-based interventions on caregiver burden (SMD = \u22120.19, 95% CI: \u22120.36 to \u22120.01). However, sensitivity analysis concluded that the effect was very small or nearly absent. Additionally, there was no statistically significant effect on QoL (SMD = 0.15, 95% CI: \u22120.05 to 0.36).<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1478951525100370_sec4d\">\n\t    <jats:title>Significance of results<\/jats:title>\n\t    <jats:p>Web-based interventions did not significantly reduce caregiver burden or improve caregivers\u2019 QoL. To improve caregiver burden and QoL in the future, comprehensive and tailored web-based interventions for this population are needed.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/s1478951525100370","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T03:39:18Z","timestamp":1752809958000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Effects of web-based interventions on cancer caregivers\u2019 burden and quality of life: A systematic review and meta-analysis"],"prefix":"10.1017","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1495-5153","authenticated-orcid":false,"given":"Myoungsuk","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4289-3188","authenticated-orcid":false,"given":"Kelly R.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorinda Adaire","family":"Coombs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"key":"S1478951525100370_ref9","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587"},{"key":"S1478951525100370_ref18","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1059605"},{"key":"S1478951525100370_ref28","unstructured":"National Alliance for Caregiving (2016) Cancer caregiving in the U.S.: an intense, episodic, and challenging care experience. https:\/\/www.caregiving.org\/wp-content\/uploads\/2022\/11\/CancerCaregivingReport_FINAL_June-17-2016.pdf (accessed 12 June, 2024 )."},{"key":"S1478951525100370_ref33","unstructured":"Sch\u00fcnemann, H , Bro\u017cek, J , Guyatt, G , et al. (2013) The GRADE handbook. https:\/\/gdt.gradepro.org\/app\/handbook\/handbook.html (accessed 12 June, 2024 )."},{"key":"S1478951525100370_ref37","first-page":"1","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"S1478951525100370_ref22","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol29020067"},{"key":"S1478951525100370_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5917"},{"key":"S1478951525100370_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djad075"},{"key":"S1478951525100370_ref17","doi-asserted-by":"publisher","DOI":"10.1188\/15.ONF.156-164"},{"key":"S1478951525100370_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2019.104003"},{"key":"S1478951525100370_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2022.104179"},{"key":"S1478951525100370_ref24","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2023.1180317"},{"key":"S1478951525100370_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4583"},{"key":"S1478951525100370_ref40","volume-title":"The Impact of a Web-based Psychological Self-help Intervention for Partners of Cancer Patients on Self-compassion","author":"Theiling","year":"2016"},{"key":"S1478951525100370_ref16","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S135372"},{"key":"S1478951525100370_ref39","doi-asserted-by":"publisher","DOI":"10.4103\/2347-5625.135811"},{"key":"S1478951525100370_ref41","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-023-10919-x"},{"key":"S1478951525100370_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2015.09.002"},{"key":"S1478951525100370_ref38","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000438"},{"key":"S1478951525100370_ref13","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2012.000690"},{"key":"S1478951525100370_ref14","first-page":"1","article-title":"Feasibility, useability and acceptability of technology-based interventions for informal cancer carers: a systematic review","volume":"18","author":"Heynsbergh","year":"2018","journal-title":"Journal BMC Cancer"},{"key":"S1478951525100370_ref21","doi-asserted-by":"publisher","DOI":"10.5334\/ijic.2944"},{"key":"S1478951525100370_ref29","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"S1478951525100370_ref31","unstructured":"Ryan, R and Hill, S (2016) How to GRADE the quality of the evidence. Cochrane Consumers and Communication Group. Version 3.0. http:\/\/www.cccrg.cochrane.org\/author-resources (accessed 12 June, 2024 )."},{"key":"S1478951525100370_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/pon.6301"},{"key":"S1478951525100370_ref36","doi-asserted-by":"publisher","DOI":"10.1186\/1472-684X-10-21"},{"key":"S1478951525100370_ref15","unstructured":"Higgins, JPT , Thomas, J , Chandler, J , et al. (2023) Cochrane Handbook for Systematic Reviews of Interventions version 6.4. http:\/\/www.training.cochrane.org\/handbook (accessed 15 June, 2024 )."},{"key":"S1478951525100370_ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4293-z"},{"key":"S1478951525100370_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/esmoopen-2020-000862"},{"key":"S1478951525100370_ref34","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_201397"},{"key":"S1478951525100370_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/02692163211066736"},{"key":"S1478951525100370_ref35","first-page":"12","article-title":"Cancer statistics, 2024","volume":"74","author":"Siegel","year":"2024","journal-title":"Journal for Clinicians"},{"key":"S1478951525100370_ref19","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1597"},{"key":"S1478951525100370_ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-022-07441-4"},{"key":"S1478951525100370_ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-021-06051-w"},{"key":"S1478951525100370_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-021-06555-5"},{"key":"S1478951525100370_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnss.2020.07.012"},{"key":"S1478951525100370_ref42","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-017-0628-6"},{"key":"S1478951525100370_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e21243"},{"key":"S1478951525100370_ref11","doi-asserted-by":"publisher","DOI":"10.1037\/a0034216"},{"key":"S1478951525100370_ref12","doi-asserted-by":"publisher","DOI":"10.1188\/17.ONF.765-775"},{"key":"S1478951525100370_ref27","doi-asserted-by":"publisher","DOI":"10.24198\/jnc.v1i3.18516"}],"container-title":["Palliative and Supportive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1478951525100370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T03:39:20Z","timestamp":1752809960000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1478951525100370\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":42,"alternative-id":["S1478951525100370"],"URL":"https:\/\/doi.org\/10.1017\/s1478951525100370","relation":{},"ISSN":["1478-9515","1478-9523"],"issn-type":[{"value":"1478-9515","type":"print"},{"value":"1478-9523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e134"}}