{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T22:05:12Z","timestamp":1769033112664,"version":"3.49.0"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"unspecified","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951525101521_sec1a\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative Care (EORTC QLQ-C15-PAL) is designed to measure quality of life (QoL) in cancer patients receiving palliative care. The aim of this study was to translate and validate an Urdu version of the questionnaire, which was previously lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951525101521_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following formal approval from the EORTC, the QLQ-C15-PAL was translated into Urdu. Patients admitted under the palliative care service at a tertiary care center in Karachi, Pakistan, were enrolled in this cross-sectional study, and the Urdu QLQ-C15-PAL and the Edmonton Symptom Assessment Scale (ESAS) forms were administered. Performance status was assessed using the Palliative Performance Scale (PPS). Cronbach\u2019s alpha and Pearson correlation coefficients were determined to gauge reliability and validity. Concurrent and known-group validity were tested using ESAS responses and PPS assessments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951525101521_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One hundred patients with varying primary cancer sites were included. Cronbach\u2019s alpha for the overall questionnaire was 0.86 and was &gt;0.8 for all subscales except fatigue, where it was 0.697. All correlations to indicate convergent validity had coefficients &gt;0.8 and 87% of correlations between \u201cunrelated\u201d domains were weak, indicating discriminant validity. Known group validity was established and improved QoL was observed in the high PPS (&gt;40) subgroup of patients across multiple domains. However, concurrent validity was not strongly established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951525101521_sec4d\">\n                    <jats:title>Significance of results<\/jats:title>\n                    <jats:p>The Urdu QLQ-C15-PAL is a reliable and valid tool to measure QoL in cancer patients who speak Urdu. However, replication of our results in other settings is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951525101521","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T07:56:41Z","timestamp":1768982201000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Bridging the language gap in palliative oncology: A translation and validation of the Urdu version of the EORTC QLQ-C15-PAL"],"prefix":"10.1017","volume":"24","author":[{"given":"M. Abdullah","family":"Jamil","sequence":"first","affiliation":[{"name":"Aga Khan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5076-3643","authenticated-orcid":false,"given":"Syed Balaj Ali","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Aga Khan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aisha","family":"Ambreen","sequence":"additional","affiliation":[{"name":"Aga Khan University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2215-1412","authenticated-orcid":false,"given":"Asra","family":"Taj","sequence":"additional","affiliation":[{"name":"Aga Khan University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismat","family":"Jabeen","sequence":"additional","affiliation":[{"name":"Aga Khan University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1059-9764","authenticated-orcid":false,"given":"Habiba","family":"Zaheer","sequence":"additional","affiliation":[{"name":"Aga Khan University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hunza","family":"Asher","sequence":"additional","affiliation":[{"name":"Aga Khan University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahnoor","family":"Javed","sequence":"additional","affiliation":[{"name":"Aga Khan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Mahmud","sequence":"additional","affiliation":[{"name":"Aga Khan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Atif","family":"Waqar","sequence":"additional","affiliation":[{"name":"Aga Khan University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2026,1,21]]},"reference":[{"key":"S1478951525101521_ref8","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2022.23.11.3611"},{"key":"S1478951525101521_ref11","unstructured":"Language data for Pakistan (2023). https:\/\/translatorswithoutborders.org\/language-data-for-pakistan\/ (accessed 25 November 2025 )"},{"key":"S1478951525101521_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2014.11.299"},{"key":"S1478951525101521_ref6","doi-asserted-by":"publisher","DOI":"10.1177\/1049909118760781"},{"key":"S1478951525101521_ref1","doi-asserted-by":"publisher","DOI":"10.1080\/17549507.2024.2324905"},{"key":"S1478951525101521_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951516000195"},{"key":"S1478951525101521_ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s005200050212"},{"key":"S1478951525101521_ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12904-023-01195-4"},{"key":"S1478951525101521_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-012-0261-0"},{"key":"S1478951525101521_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(20000501)88:9<2164::AID-CNCR24>3.0.CO;2-5"},{"key":"S1478951525101521_ref25","doi-asserted-by":"publisher","DOI":"10.1186\/1472-684X-11-16"},{"key":"S1478951525101521_ref21","doi-asserted-by":"publisher","DOI":"10.1177\/014662169501900308"},{"key":"S1478951525101521_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1801"},{"key":"S1478951525101521_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2005.06.022"},{"key":"S1478951525101521_ref9","doi-asserted-by":"publisher","DOI":"10.1186\/1472-684X-7-10"},{"key":"S1478951525101521_ref3","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2018.0141"},{"key":"S1478951525101521_ref4","doi-asserted-by":"publisher","DOI":"10.1177\/082585979100700202"},{"key":"S1478951525101521_ref14","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-0175-9"},{"key":"S1478951525101521_ref23","unstructured":"Using multivariate statistics, 5th ed. (2007). https:\/\/psycnet.apa.org\/record\/2006-03883-000 (accessed 25 November 2025 )"},{"key":"S1478951525101521_ref12","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2008.1.465"},{"key":"S1478951525101521_ref16","unstructured":"Palliative care (2020). https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/palliative-care (accessed 25 November 2025 )"},{"key":"S1478951525101521_ref19","unstructured":"Scoring Manual (2017, October 17). https:\/\/qol.eortc.org\/manual\/scoring-manual\/ (accessed 25 November 2025 )"},{"key":"S1478951525101521_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-013-0511-9"},{"key":"S1478951525101521_ref22","unstructured":"Urdu Language (URD) \u2013 L1 & L2 Speakers, Status, Map, Endangered Level & Official Use | Ethnologue Free (2025). https:\/\/www.ethnologue.com\/language\/urd\/ (accessed 25 November 2025 )"},{"key":"S1478951525101521_ref24","unstructured":"Worldwide cancer data (2022). https:\/\/www.wcrf.org\/preventing-cancer\/cancer-statistics\/worldwide-cancer-data\/ (accessed 25 November 2025 )"},{"key":"S1478951525101521_ref26","doi-asserted-by":"publisher","DOI":"10.1186\/s41687-021-00354-6"}],"container-title":["Palliative and Supportive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1478951525101521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T07:56:43Z","timestamp":1768982203000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1478951525101521\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":26,"alternative-id":["S1478951525101521"],"URL":"https:\/\/doi.org\/10.1017\/s1478951525101521","relation":{},"ISSN":["1478-9515","1478-9523"],"issn-type":[{"value":"1478-9515","type":"print"},{"value":"1478-9523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e41"}}