{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:11:48Z","timestamp":1777414308838,"version":"3.51.4"},"reference-count":49,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"unspecified","delay-in-days":57,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951526101801_sec1a\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>People with serious illnesses often experience spiritual and emotional pain, manifesting in conditions such as depression, anxiety, and demoralization. Emerging research in psychedelic-assisted therapy has shown efficacy in treating these conditions. Despite evidence that psychedelics frequently occasion mystical\/spiritual experiences in participants, there has been little research on support for spiritual, existential, religious, and theological needs, including the use of chaplains on therapeutic teams. Spiritual wellbeing outcomes have been inconsistently used and reported on in current psychedelics studies. The aims of this article are to identify and review patient-centered outcome measures focused on spiritual wellbeing for use in psychedelic research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101801_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature review of instruments was conducted, with 286 articles included, identifying spiritual wellbeing measures within the palliative care population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101801_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three measures were selected for inclusion: Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being 12- Item Scale (FACIT-Sp-12), European Organization for Research and Treatment of Cancer Quality of Life Spiritual Well-being Questionnaire (EORTC QLQ-SWB-32), and the National Institutes of Health Healing Experience of All Life Stressors (NIH-HEALS). Instrument development, psychometric properties, and use in research for each are discussed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101801_sec4d\">\n                    <jats:title>Significance of Results<\/jats:title>\n                    <jats:p>Suitability in the context of psychedelic-assisted therapy with the palliative care population includes strong reliability and validity, and they should be accessible to people with various spiritual traditions, practices, and sources of connection. They should be patient-centered in their development, involve multiple stakeholders, and be appropriate for use with palliative care populations. According to these criteria and its orientation toward identifying spiritual change in the context of serious illness, the NIH-HEALS is recommended for wider use in psychedelic-assisted therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951526101801","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:36:12Z","timestamp":1772170572000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Spiritual wellbeing in psychedelic-assisted therapy with palliative care populations: An analysis of outcome measures"],"prefix":"10.1017","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0000-3630","authenticated-orcid":false,"given":"Stephen","family":"Lewis","sequence":"first","affiliation":[{"name":"University of Maryland"},{"name":"University of California"},{"name":"Emory Center for Psychedelics and Spirituality, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"S1478951526101801_ref38","doi-asserted-by":"publisher","DOI":"10.1037\/a0034805"},{"key":"S1478951526101801_ref46","unstructured":"Wheelwright, S , Bjordal, K , Bottomley, A , et al. (2021) EORTC quality of life group guidelines for developing questionnaire modules. https:\/\/qol.eortc.org\/manual\/the-module-development-guidelines-2021\/ (accessed 28 June 2025 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A (2023) The safety, feasibility, and acceptability of psilocybin combined with multidisciplinary palliative care in demoralized cancer survivors with chronic pain (P-PC) (Clinical trial registration No. NCT05506982). clinicaltrials.gov. https:\/\/clinicaltrials.gov\/study\/NCT05506982 (accessed 27 November 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CS (2025) Pragmatic trial of psilocybin therapy in palliative care (PT2PC): a multicenter triple-blind phase 2 randomized controlled trial of psilocybin therapy for demoralized adults near the end of life (Clinical trial registration No. NCT05403086). clinicaltrials.gov. https:\/\/clinicaltrials.gov\/study\/NCT05403086 (accessed 27 November 2025)"},{"key":"S1478951526101801_ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0457-5"},{"key":"S1478951526101801_ref7","unstructured":"Beaussant, Y (2023) Pilot study of psilocybin-assisted therapy for demoralization in patients receiving hospice care - PATH study (Clinical trial registration No. NCT04950608). clinicaltrials.gov. https:\/\/clinicaltrials.gov\/study\/NCT04950608(accessed 27 November 2025)"},{"key":"S1478951526101801_ref16","doi-asserted-by":"publisher","DOI":"10.1080\/08854726.2024.2368999"}],"container-title":["Palliative and Supportive 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Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e75"}}