{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T05:59:45Z","timestamp":1772085585265,"version":"3.50.1"},"reference-count":46,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"unspecified","delay-in-days":56,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951526101977_sec1a\">\n                    <jats:title\/>\n                    <jats:p>Psychedelic therapies are gaining attention as a novel therapy for existential distress in cancer patients. However, such treatments are often stigmatized and the views of support networks are unknown. Caregivers play an essential role in supporting the wellbeing and decision-making of people with cancer. In the context of a trial investigating psychedelic therapy for cancer patients, understanding the experience of the caregiver is important.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101977_sec2b\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objectives of this research were to investigate the hopes, beliefs, perceptions, and experience of caregivers for advanced cancer patients undergoing a trial investigating a psychedelic-assisted therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101977_sec3c\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Semi-structured interviews asked 15 caregivers about their experience at baseline and 1 month after their close associate had completed treatment in a feasibility trial where participants were randomized to receive either lysergic acid diethylamide (LSD) microdoses or placebo alongside meaning-centered psychotherapy (MCP). Blinded to condition, reflexive thematic analysis was used to analyze interview transcripts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101977_sec4d\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study demonstrates the importance of bidirectional influences between caregiver and patient; the experience of one influences the experience of both. Caregivers were generally supportive of their close associate participating in a psychedelic-assisted trial, although some admitted hesitancy in them taking part. Caregivers described a desire to make the most of now, referring to the role of LSD microdose-assisted MCP as a means of accessing hope, improving the dyad relationship, and reducing existential distress.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526101977_sec5e\">\n                    <jats:title>Significance of Results<\/jats:title>\n                    <jats:p>Participation in trials investigating psychedelic-assisted MCP may offer hope for patients and their caregivers. Given the bidirectional relationship in wellbeing between cancer dyads, caregivers should be included alongside patients in such trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951526101977","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:01:24Z","timestamp":1772078484000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["It\u2019s all about the relationship: The caregiver experience of supporting a person with advanced cancer going through an LSD microdosing trial"],"prefix":"10.1017","volume":"24","author":[{"given":"Fiona","family":"Cottam","sequence":"first","affiliation":[{"name":"University of Auckland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alesha","family":"Wells","sequence":"additional","affiliation":[{"name":"University of 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