{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:18:50Z","timestamp":1785406730252,"version":"3.56.0"},"reference-count":31,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"unspecified","delay-in-days":159,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951526102740_sec1a\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cancer-related fatigue (CRF) is a distressing symptom in terminally ill patients with cancer. While many studies have been conducted on the relationship between fatigue and quality of life (QOL) among patients undergoing treatment, only a few have been conducted to measure fatigue from multiple perspectives or clarify its impact on patients in advanced stages or those receiving palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526102740_sec2b\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine the impact of fatigue on QOL in terminally ill patients with cancer, using a questionnaire that measures CRF from 3 perspectives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526102740_sec3c\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>CRF and QOL were measured using the Cancer Fatigue Scale (CFS) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative (EORTCQLQ-C15-PAL), respectively, and the correlation between them was evaluated. Web-based questionnaires were completed by patients receiving hospice and palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526102740_sec4d\">\n                    <jats:title>Significance of results<\/jats:title>\n                    <jats:p>\n                      Twenty-nine participants provided valid responses. Median CFS and global health status\/QOL scores were as follows: total fatigue 25.0, physical fatigue 11.0, affective fatigue 9.0, cognitive fatigue 5.0, and global health status\/QOL 50.0. QOL showed significant correlations with total fatigue (\n                      <jats:italic>rs<\/jats:italic>\n                      \u00a0=\u00a0\u22120.44,\n                      <jats:italic>p\u00a0=<\/jats:italic>\n                      \u00a00.017, 95% CI: \u22120.70, \u22120.09) and physical fatigue (\n                      <jats:italic>rs<\/jats:italic>\n                      \u00a0=\u00a0\u22120.38,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.038, 95% CI: \u22120.66, \u22120.02), but none with affective fatigue (\n                      <jats:italic>rs<\/jats:italic>\n                      \u00a0=\u00a0\u22120.02,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.917, 95% CI: \u22120.38, 0.35) and cognitive fatigue (\n                      <jats:italic>rs<\/jats:italic>\n                      \u00a0=\u00a0\u22120.33,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.074, 95% CI: \u22120.63, 0.03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526102740_sec5e\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Of the 3 aspects of fatigue, physical fatigue may be most closely related to QOL; however, its accurate assessment may depend on the scale used. Therefore, it is necessary to select an appropriate scale for patients with terminal cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951526102740","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T13:40:00Z","timestamp":1781012400000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Tendencies in the association between fatigue and quality of life in terminally ill patients with cancer admitted to a palliative care unit"],"prefix":"10.1017","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5251-734X","authenticated-orcid":false,"given":"Mizuki","family":"Matsuda","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ww21r56","id-type":"ROR","asserted-by":"publisher"}],"name":"Niigata University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Koyama","sequence":"additional","affiliation":[{"name":"Niigata University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nao","family":"Seki","sequence":"additional","affiliation":[{"name":"Niigata University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayuri","family":"Sakai","sequence":"additional","affiliation":[{"name":"Niigata University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"S1478951526102740_ref4","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3989286"},{"key":"S1478951526102740_ref12","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1075.105686"},{"key":"S1478951526102740_ref20","unstructured":"NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines\u00ae) (2025) Cancer-Related Fatigue Version 2.2025. https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/fatigue.pdf (accessed 1 September 2025 )."},{"key":"S1478951526102740_ref28","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10222"},{"key":"S1478951526102740_ref19","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2023.24.3.769"},{"key":"S1478951526102740_ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2006.03754.x"},{"key":"S1478951526102740_ref3","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"S1478951526102740_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2006.08.001"},{"key":"S1478951526102740_ref26","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11742"},{"key":"S1478951526102740_ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-016-3275-2"},{"key":"S1478951526102740_ref9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0134022"},{"key":"S1478951526102740_ref16","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn537"},{"key":"S1478951526102740_ref29","first-page":"4","article-title":"Patient, caregiver, and oncologist perceptions of cancer-related fatigue: Results of a tripart assessment survey","volume":"34","author":"Vogelzang","year":"1997","journal-title":"The Fatigue Coalition. 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Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e161"}}