{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:10:22Z","timestamp":1788970222358,"version":"build-2803163510"},"reference-count":45,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"unspecified","delay-in-days":251,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951526103411_sec1a\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the relationship between pain (including neuropathic pain [NP]), functional impairment, and anxiety\/depression among Nigerian cancer patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526103411_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study enrolled 126 adult cancer patients at a Nigerian teaching hospital. Pain intensity, NP (painDETECT), functional impairment (Sheehan Disability Scale), and anxiety\/depression (Hospital Anxiety and Depression Scale, HADS) were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526103411_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Prevalence rates were 37.3% for anxiety and 35.7% for depression. Pain was reported by 82% of patients (predominantly mild), while NP occurred in 23%. Bivariate and correlation analyses showed no significant association between pain (including NP) and anxiety\/depression (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a00.05). However, functional impairment was strongly correlated with both outcomes (HADS-A:\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.470; HADS-D:\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.675;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Multivariate regression identified functional impairment as the strongest independent predictor of anxiety (odds ratio [OR]\u00a0=\u00a07.537) and depression (OR\u00a0=\u00a08.625). Pain intensity and NP were not retained as significant predictors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526103411_sec4d\">\n                    <jats:title>Significance of results<\/jats:title>\n                    <jats:p>Functional impairment, not pain nor NP, independently predicts anxiety and depression in Nigerian cancer patients. Routine functional screening may be more clinically useful than pain-focused assessments for identifying psychological distress in resource-limited oncology settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951526103411","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:23:50Z","timestamp":1788967430000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Functional impairment, not pain, predicts anxiety and depression in Nigerian cancer patients: A cross-sectional study of nociceptive and neuropathic pain"],"prefix":"10.1017","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8395-8967","authenticated-orcid":false,"given":"Ogochukwu","family":"Izuegbuna","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03bag5a72","id-type":"ROR","asserted-by":"publisher"}],"name":"Lautech Teaching 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Ilorin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"S1478951526103411_ref13","doi-asserted-by":"publisher","DOI":"10.32768\/abc.2024112118-125"},{"key":"S1478951526103411_ref24","doi-asserted-by":"publisher","DOI":"10.3332\/ecancer.2023.1650"},{"key":"S1478951526103411_ref39","doi-asserted-by":"publisher","DOI":"10.1002\/hup.2500"},{"key":"S1478951526103411_ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijans.2019.100166"},{"key":"S1478951526103411_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e31822bb35b"},{"key":"S1478951526103411_ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-024-01248-7"},{"key":"S1478951526103411_ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2021.04.008"},{"key":"S1478951526103411_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/27697061.2024.2353289"},{"key":"S1478951526103411_ref22","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S561284"},{"key":"S1478951526103411_ref16","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.972360"},{"key":"S1478951526103411_ref28","doi-asserted-by":"publisher","DOI":"10.1093\/9780197675250.003.0005"},{"key":"S1478951526103411_ref6","first-page":"497","article-title":"Measurement 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Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e220"}}