{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:06:11Z","timestamp":1789383971276,"version":"build-2803163510"},"reference-count":40,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"unspecified","delay-in-days":256,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1478951526103496_sec1a\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Patients with idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) frequently experience respiratory symptoms and declines in activities of daily living (ADL) and quality of life (QOL). However, effective treatment and palliative care strategies remain limited. This study aimed to clarify physical and psychological distress and to evaluate 1-year symptom changes in patients with IPF and PPF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526103496_sec2b\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients with IPF or PPF were recruited and evaluated at registration (T0), 26 weeks (T1), and 52 weeks (T2). Symptoms, ADL, QOL, depressive condition, laboratory findings, and other factors were assessed throughout the 52-week follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526103496_sec3c\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 70 patients, 32 had IPF and 38 had PPF. Repeated-measures analysis of variance showed that dyspnea in patients with IPF worsened from T1 to T2 (p = 0.02). In contrast, cough, which is one of the major symptoms in PPF worsened from T0 to T1 (p = 0.01) and T0 to T2 (p = 0.02). QOL in patients with PPF also declined from T0 to T1 (p = 0.03).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1478951526103496_sec4d\">\n                    <jats:title>Significance of results<\/jats:title>\n                    <jats:p>Patients with IPF and PPF demonstrated several clinical signs and symptoms. In this 1-year follow-up study, dyspnea tended to be worse in patients with IPF and cough in PPF patients, and QOL was temporarily worse in PPF patients. Respiratory symptoms are directly related to the patient\u2019s daily life and lead to reduced QOL. Therefore, further long-term studies in this population are required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1478951526103496","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:32:37Z","timestamp":1789381957000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of distress and changes over time among patients with idiopathic pulmonary fibrosis and progressive pulmonary fibrosis"],"prefix":"10.1017","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6440-0816","authenticated-orcid":false,"given":"Tomoko","family":"Umimura","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01692sz90","id-type":"ROR","asserted-by":"publisher"}],"name":"Juntendo University Faculty of Medicine and Graduate School of Medicine"},{"id":[{"id":"https:\/\/ror.org\/01692sz90","id-type":"ROR","asserted-by":"publisher"}],"name":"Juntendo Tokyo Koto Geriatric Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3665-0537","authenticated-orcid":false,"given":"Koji","family":"Sugano","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01692sz90","id-type":"ROR","asserted-by":"publisher"}],"name":"Juntendo University Faculty of Medicine and Graduate School of Medicine"},{"id":[{"id":"https:\/\/ror.org\/01692sz90","id-type":"ROR","asserted-by":"publisher"}],"name":"Juntendo Tokyo Koto Geriatric Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Matsuno","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01692sz90","id-type":"ROR","asserted-by":"publisher"}],"name":"Juntendo University Faculty of Medicine and Graduate School of Medicine"},{"id":[{"id":"https:\/\/ror.org\/01692sz90","id-type":"ROR","asserted-by":"publisher"}],"name":"Juntendo Tokyo Koto Geriatric Medical 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Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use and\/or adaptation of the article.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e223"}}