{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T06:31:01Z","timestamp":1715841061714},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJEM"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A child presenting with petechiae and fever is assumed to have meningococcemia or another form of bacterial sepsis and therefore to require antibiotics, blood cultures, cerebrospinal fluid analysis and hospital admission. A review of the literature challenges this statement and suggests that a child presenting with purpura (or petechiae), an ill appearance and delayed capillary refill time or hypotension should be admitted and treated for meningococcal disease without delay. Conversely, a child with a petechial rash, which is confined to the distribution of the superior vena cava, is unlikely to have meningococcal disease. Outpatient therapy in this context is appropriate. In other children, a reasonable approach would be to draw blood for culture and C-reactive protein (CRP) while administering antibiotics. If the CRP is normal, these children could be discharged to follow-up in 1 day, whereas children with CRP values greater than 6 mg\/L would be admitted.<\/jats:p>","DOI":"10.1017\/s1481803500010617","type":"journal-article","created":{"date-parts":[[2016,7,15]],"date-time":"2016-07-15T06:01:05Z","timestamp":1468562465000},"page":"479-482","source":"Crossref","is-referenced-by-count":6,"title":["Pediatric myth: fever and petechiae"],"prefix":"10.1007","volume":"10","author":[{"given":"Martin D.","family":"Klinkhammer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James E.","family":"Colletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,5,21]]},"reference":[{"key":"S1481803500010617_ref003","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1542\/peds.84.6.1051","volume":"84","year":"1989","journal-title":"Pediatrics"},{"key":"S1481803500010617_ref002","first-page":"224","volume":"8","year":"1989","journal-title":"Pediatr Infect Dis J"},{"key":"S1481803500010617_ref001","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1542\/peds.74.1.77","volume":"74","year":"1984","journal-title":"Pediatrics"},{"key":"S1481803500010617_ref011","doi-asserted-by":"publisher","DOI":"10.1136\/adc.85.2.160"},{"key":"S1481803500010617_ref009","doi-asserted-by":"publisher","DOI":"10.1136\/adc.83.6.506"},{"key":"S1481803500010617_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)80065-0"},{"key":"S1481803500010617_ref008","volume":"103","year":"1999","journal-title":"Pediatrics"},{"key":"S1481803500010617_ref007","doi-asserted-by":"crossref","first-page":"134","DOI":"10.5694\/j.1326-5377.2003.tb05106.x","volume":"178","year":"2003","journal-title":"Med J Aust"},{"key":"S1481803500010617_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80290-X"},{"key":"S1481803500010617_ref005","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1974.02110210023003"},{"key":"S1481803500010617_ref010","doi-asserted-by":"publisher","DOI":"10.1136\/adc.85.3.218"}],"container-title":["CJEM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1481803500010617","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T03:44:02Z","timestamp":1656819842000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1481803500010617\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":11,"journal-issue":{"issue":"05","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S1481803500010617"],"URL":"https:\/\/doi.org\/10.1017\/s1481803500010617","relation":{},"ISSN":["1481-8035","1481-8043"],"issn-type":[{"value":"1481-8035","type":"print"},{"value":"1481-8043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}