{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:53:28Z","timestamp":1768784008333,"version":"3.49.0"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2012,1,5]],"date-time":"2012-01-05T00:00:00Z","timestamp":1325721600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dev Orig Health Dis"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p>We have determined the influence of the severity of retinopathy of prematurity (ROP) on development at 3 years of age in infants &lt;29 weeks gestation from a population-based cohort. Primary analysis of surviving infants born &lt;29 weeks gestational age (GA) from 1998 to 2001 in New South Wales and the Australian Capital Territory were grouped according to stage of ROP. Infants with periventricular leukomalacia, Grade III or IV intraventricular haemorrhage, hydrocephalus, major congenital abnormalities, Stage 4 or 5 ROP, cerebral palsy or a severe hearing impairment were excluded. Infants with Stage 3 ROP were matched for GA, birthweight and gender to those with no ROP, Stage 1 and Stage 2 ROP. The four groups were then compared for their 3-year-old developmental outcome, using the Griffiths Mental Development Scale. Development was also compared for those infants with Stage 3 ROP who were either treated or not treated with laser therapy. A secondary multivariate regression analysis on developmental outcome was performed with all infants included in the analysis. In neurologically comparable groups and in the multivariate analysis, there was no association between ROP and developmental outcome. There was also no difference in the Griffiths assessment at 3 years between those who were or were not treated for severe ROP. Neither severity of ROP nor treatment for severe ROP were related to developmental outcome at 3 years of age in a large population-based cohort of infants born &lt;29 weeks gestation.<\/jats:p>","DOI":"10.1017\/s2040174411000766","type":"journal-article","created":{"date-parts":[[2012,1,6]],"date-time":"2012-01-06T05:17:44Z","timestamp":1325827064000},"page":"116-122","source":"Crossref","is-referenced-by-count":12,"title":["Developmental outcome in preterm infants &lt;29 weeks gestation with \u2a7d Stage 3 retinopathy of prematurity (ROP): relationship to severity of ROP"],"prefix":"10.1017","volume":"3","author":[{"given":"D.A.","family":"Todd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T-A.","family":"Goyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rochefort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,1,5]]},"reference":[{"key":"S2040174411000766_manual_ref-16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.1993.tb00511.x"},{"key":"S2040174411000766_manual_ref-31","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/S0042-6989(97)00399-4","article-title":"Eye movements, prematurity and developmental co-ordination disorder","volume":"38","author":"Langaas","year":"1998","journal-title":"Vision Res"},{"key":"S2040174411000766_manual_ref-39","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.1.e1"},{"key":"S2040174411000766_manual_ref-32","first-page":"354","article-title":"Finishing first grade: a study of school achievement in very-low-birth-weight children","volume":"41","author":"Schraeder","year":"1992","journal-title":"Nurs Res"},{"key":"S2040174411000766_manual_ref-25","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1111\/j.1469-8749.2010.03730.x","article-title":"Do healthy preterm children need neuropsychological follow-up?","volume":"52","author":"Dall'Oglio","year":"2010","journal-title":"Dev Med Child Neurol"},{"key":"S2040174411000766_manual_ref-18","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.5.998"},{"key":"S2040174411000766_manual_ref-29","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/bjo.83.2.143","article-title":"Ophthalmological follow up of preterm infants: a population based, prospective study of visual acuity and strabismus","volume":"83","author":"Holmstrom","year":"1999","journal-title":"Br J Opthalmol"},{"key":"S2040174411000766_manual_ref-9","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.7.991"},{"key":"S2040174411000766_manual_ref-33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1469-8749.1996.tb12081.x","article-title":"Development of a regional cohort of very-low-birthweight children at six years: cognitive abilities are associated with neurological disability and social background","volume":"38","author":"Dammann","year":"1996","journal-title":"Dev Med Child Neurol"},{"key":"S2040174411000766_manual_ref-34","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(99)00056-0"},{"key":"S2040174411000766_manual_ref-28","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1136\/bjo.81.11.935","article-title":"Prospective study of New Zealand infants with birth weight less than 1500 g and screened for retinopathy of prematurity: visual outcome at age 7\u20138 years","volume":"81","author":"Darlow","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"S2040174411000766_manual_ref-2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0378-3782(94)01597-I","article-title":"Extremely low birth weight and control infants at 2 years corrected age: a comparison of intellectual abilities, motor performance, growth and health","volume":"40","author":"O'Callaghan","year":"1995","journal-title":"Early Hum Dev"},{"key":"S2040174411000766_manual_ref-12","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1136\/bjo.83.5.514","article-title":"Risk factors for strabismus in children born before 32 weeks\u2019 gestation","volume":"83","author":"Pennefeather","year":"1999","journal-title":"Br J Ophthalmol"},{"key":"S2040174411000766_manual_ref-6","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1136\/bjo.67.3.170","article-title":"Myopia in premature babies with and without retinopathy of prematurity","volume":"67","author":"Nissenkorn","year":"1983","journal-title":"Br J Ophthalmol"},{"key":"S2040174411000766_manual_ref-35","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/mrdd.10005","article-title":"Perinatal infection, fetal inflammatory response, white matter damage, and cognitive limitations in children born preterm","volume":"8","author":"Dammann","year":"2002","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"S2040174411000766_manual_ref-17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211228"},{"key":"S2040174411000766_manual_ref-21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.1994.tb01690.x"},{"key":"S2040174411000766_manual_ref-15","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2006.02.011"},{"key":"S2040174411000766_manual_ref-19","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/S0140-6736(95)92475-2","article-title":"Transcutaneous oxygen levels in retinopathy of prematurity","volume":"346","author":"Cunningham","year":"1995","journal-title":"Lancet"},{"key":"S2040174411000766_manual_ref-23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1999.tb00193.x"},{"key":"S2040174411000766_manual_ref-26","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1136\/adc.2007.134692","article-title":"Developmental coordination disorder in \u2018apparently normal\u2019 school children born extremely preterm","volume":"94","author":"Goyen","year":"2009","journal-title":"Arch Dis Child"},{"key":"S2040174411000766_manual_ref-5","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1982.01030030258004"},{"key":"S2040174411000766_manual_ref-8","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1136\/bjo.67.5.302","article-title":"Ocular morbidity in infants of very low birth weight","volume":"67","author":"Keith","year":"1983","journal-title":"Br J Opthalmol"},{"key":"S2040174411000766_manual_ref-24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.06.043"},{"key":"S2040174411000766_manual_ref-11","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.096479"},{"key":"S2040174411000766_manual_ref-20","doi-asserted-by":"publisher","DOI":"10.3928\/0191-3913-19970901-07"},{"key":"S2040174411000766_manual_ref-7","first-page":"446","article-title":"Visual outcome and effect of treatment in Stage 3 developing retrolental fibroplasia","volume":"66","author":"Keith","year":"1982","journal-title":"Opthalmology"},{"key":"S2040174411000766_manual_ref-22","first-page":"171","article-title":"Patent ductus arteriosus and retinopathy of prematurity in infants below 27 weeks gestation","volume":"24","author":"John","year":"1988","journal-title":"Aust Paediatr J"},{"key":"S2040174411000766_manual_ref-30","doi-asserted-by":"publisher","DOI":"10.1006\/jecp.1996.2326"},{"key":"S2040174411000766_manual_ref-38","doi-asserted-by":"crossref","first-page":"F182","DOI":"10.1136\/fn.83.3.F182","article-title":"Sex differences in outcomes of very low birthweight infants: the newborn male disadvantage","volume":"83","author":"Stevenson","year":"2000","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"S2040174411000766_manual_ref-4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)74860-3"},{"key":"S2040174411000766_manual_ref-13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1136\/bjo.2005.081653","article-title":"Contrast sensitivity in 10 year old preterm and full term children: a population based study","volume":"90","author":"Larsson","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"S2040174411000766_manual_ref-1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.6.1216"},{"key":"S2040174411000766_manual_ref-27","doi-asserted-by":"crossref","first-page":"F249","DOI":"10.1136\/adc.2002.023374","article-title":"Ophthalmic impairment at 7 years of age in children born very preterm","volume":"89","author":"Cooke","year":"2004","journal-title":"Arch Dise Child Fetal Neonatal Ed"},{"key":"S2040174411000766_manual_ref-36","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1001\/jama.289.9.1124","article-title":"Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms","volume":"289","author":"Schmidt","year":"2003","journal-title":"JAMA"},{"key":"S2040174411000766_manual_ref-37","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1542\/peds.100.4.633","article-title":"Outcome of extremely low birth weight infants (500 to 999 grams) over a 12-year period","volume":"100","author":"Piecuch","year":"1997","journal-title":"Pediatrics"},{"key":"S2040174411000766_manual_ref-3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80043-5"},{"key":"S2040174411000766_manual_ref-14","doi-asserted-by":"publisher","DOI":"10.1159\/000027442"},{"key":"S2040174411000766_manual_ref-10","author":"Griffiths","year":"1970","journal-title":"The Abilities of Young Children. A Comprehensive System of Mental Measurement for the First Eight Years of Life"}],"container-title":["Journal of Developmental Origins of Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2040174411000766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T19:39:56Z","timestamp":1750448396000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2040174411000766\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,5]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S2040174411000766"],"URL":"https:\/\/doi.org\/10.1017\/s2040174411000766","relation":{},"ISSN":["2040-1744","2040-1752"],"issn-type":[{"value":"2040-1744","type":"print"},{"value":"2040-1752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,5]]}}}