{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:48:56Z","timestamp":1791985736845,"version":"4.4.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2018,3,12]],"date-time":"2018-03-12T00:00:00Z","timestamp":1520812800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol Psychiatr Sci"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:p>A substantial proportion of people with mental health conditions do not adhere to prescribed pharmacological treatments. Poor adherence is probably one of the most critical elements contributing to relapse in people with schizophrenia and other severe mental disorders. In order to tackle this global issue, in November 2017 the Food and Drug Administration approved a tablet formulation of the atypical antipsychotic aripiprazole embedded with a novel digital adherence-assessment device. In this commentary, we critically appraised the potential beneficial and harmful consequences of this new digital formulation of aripiprazole, and we highlighted expected implications for clinical practice.<\/jats:p>","DOI":"10.1017\/s2045796018000082","type":"journal-article","created":{"date-parts":[[2018,3,12]],"date-time":"2018-03-12T10:51:27Z","timestamp":1520851887000},"page":"227-229","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["Can a digital medicine system improve adherence to antipsychotic treatment?"],"prefix":"10.1017","volume":"27","author":[{"given":"D.","family":"Papola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Gastaldon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Ostuzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2018,3,12]]},"reference":[{"key":"S2045796018000082_ref12","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.2147\/NDT.S116029","article-title":"Usability of a novel digital medicine system in adults with schizophrenia treated with sensor-embedded tablets of aripiprazole","volume":"12","author":"Peters-Strickland","year":"2016","journal-title":"Neuropsychiatric Disease and Treatment"},{"key":"S2045796018000082_ref8","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.2147\/NDT.S143091","article-title":"A multicenter, open-label, pilot study evaluating the functionality of an integrated call center for a digital medicine system to optimize monitoring of adherence to oral aripiprazole in adult patients with serious mental illness","volume":"13","author":"Kopelowicz","year":"2017","journal-title":"Neuropsychiatric Disease and Treatment"},{"key":"S2045796018000082_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/2045125312464106"},{"key":"S2045796018000082_ref6","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.12m08222"},{"key":"S2045796018000082_ref4","doi-asserted-by":"publisher","DOI":"10.1177\/2045125314542098"},{"key":"S2045796018000082_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2005.02.020"},{"key":"S2045796018000082_ref2","unstructured":"Carson WH (2015). 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(2017). Abilify MyCite's prescribing information (labeling) notes. Retrieved 2 December 2017 from https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/207202lbl.pdf"}],"container-title":["Epidemiology and Psychiatric Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2045796018000082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,14]],"date-time":"2019-04-14T19:54:39Z","timestamp":1555271679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2045796018000082\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,12]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S2045796018000082"],"URL":"https:\/\/doi.org\/10.1017\/s2045796018000082","relation":{},"ISSN":["2045-7960","2045-7979"],"issn-type":[{"value":"2045-7960","type":"print"},{"value":"2045-7979","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,12]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2018\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}