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To address this, the objective of this study was to identify young people with persistent depressive symptoms across adolescence and young adulthood and examine the prospective associations between factors and persistent depressive symptoms in young people.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2045796024000350_sec2b\">\n\t    <jats:title>Methods<\/jats:title>\n\t    <jats:p>We used data from 6711 participants in the Avon Longitudinal Study of Parents and Children. Depressive symptoms were assessed at 12.5, 13.5, 16, 17.5, 21 and 22 years with the Short Mood and Feelings Questionnaire, and we further examined the influence of multiple biological, psychological and social factors in explaining chronic depressive symptoms.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2045796024000350_sec3c\">\n\t    <jats:title>Results<\/jats:title>\n\t    <jats:p>Using latent class growth analysis, we identified four trajectories of depressive symptoms: persistent high, persistent low, persistent moderate and increasing high. After applying several logistic regression models, we found that loneliness and feeling less connected at school were the most relevant factors for chronic course of depressive symptoms.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2045796024000350_sec4d\">\n\t    <jats:title>Conclusions<\/jats:title>\n\t    <jats:p>Our findings contribute with the identification of those children who are at highest risk for developing chronic depressive symptoms.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/s2045796024000350","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T13:11:51Z","timestamp":1719407511000},"source":"Crossref","is-referenced-by-count":3,"title":["Factors associated with chronic depressive symptoms across adolescence and young adulthood: a UK birth cohort study"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9257-1457","authenticated-orcid":false,"given":"B. 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