{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T18:18:21Z","timestamp":1780337901516,"version":"3.54.1"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"unspecified","delay-in-days":309,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol Psychiatr Sci"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:sec id=\"S2045796024000374_sec1a\">\n\t    <jats:title>Aims<\/jats:title>\n\t    <jats:p>The role of depression in subsequent infertility, miscarriage and stillbirth remains unclear. This study aimed to examine the association of a history of depression with these adverse outcomes using a longitudinal cohort study of women across their reproductive life span.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2045796024000374_sec2b\">\n\t    <jats:title>Methods<\/jats:title>\n\t    <jats:p>This study used data from participants in the Australian Longitudinal Study on Women\u2019s Health who were born in 1973\u20131978. Participants (<jats:italic>N<\/jats:italic> = 8707) were followed up every 3 years from 2000 (aged 22\u201327) to 2018 (aged 40\u201345). Information on a diagnosis of depression was collected from each survey, and antidepressant medication use was identified through pharmaceutical prescription data. Histories of infertility, miscarriage, and stillbirth were self-reported at each survey. Time-lagged log-binomial models with generalized estimating equations were used to assess the association of a history of depression up to and including in a given survey with the risk of fertility issues in the next survey.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2045796024000374_sec3c\">\n\t    <jats:title>Results<\/jats:title>\n\t    <jats:p>Women with a history of depression (excluding postnatal depression) were at higher risk of infertility [risk ratio (RR) = 1.34, 95% confidence interval (CI): 1.21\u20131.48], miscarriage (RR = 1.22, 95%CI: 1.10\u20131.34) and recurrent miscarriages (\u22652; RR = 1.39, 95%CI: 1.17\u20131.64), compared to women without a history of depression. There were too few stillbirths to provide clear evidence of an association. Antidepressant medication use did not affect the observed associations. Estimated RRs of depression with infertility and miscarriage increased with age.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2045796024000374_sec4d\">\n\t    <jats:title>Conclusions<\/jats:title>\n\t    <jats:p>A history of depression was associated with higher risk of subsequent infertility, miscarriage and recurrent miscarriages.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/s2045796024000374","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T09:30:29Z","timestamp":1730799029000},"source":"Crossref","is-referenced-by-count":4,"title":["Association of a history of depression with infertility, miscarriage and stillbirth: a longitudinal cohort study"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0023-1066","authenticated-orcid":false,"given":"Chen","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3261-5942","authenticated-orcid":false,"given":"Hsin-Fang","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4956-0124","authenticated-orcid":false,"given":"Annette J.","family":"Dobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9610-5904","authenticated-orcid":false,"given":"Gita D.","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"S2045796024000374_ref29","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.20230004"},{"key":"S2045796024000374_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2010.03351.x"},{"key":"S2045796024000374_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2016.06.058"},{"key":"S2045796024000374_ref14","unstructured":"Institute of Health Metrics and Evaluation (2023) Global Health Eata eXchange (GHDx). http:\/\/ghdx.healthdata.org\/gbd-results-tool?params=gbd-api-2019-permalink\/d780dffbe8a381b25e1416884959e88b (accessed 07 December 2023 )."},{"key":"S2045796024000374_ref16","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.116.186726"},{"key":"S2045796024000374_ref15","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.11081251"},{"key":"S2045796024000374_ref1","doi-asserted-by":"publisher","DOI":"10.2217\/WHE.15.19"},{"key":"S2045796024000374_ref18","unstructured":"Kemp, A , Paige, E and Banks, E (2023) Beginner\u2019s guide to using pharmaceutical benefits scheme data. https:\/\/nceph.anu.edu.au\/files\/Guide_to_Using_PBS_Data_20131125_0.pdf (accessed 07 December 2023 )."},{"key":"S2045796024000374_ref19","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-031912-114409"},{"key":"S2045796024000374_ref28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001356"},{"key":"S2045796024000374_ref33","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.10.2580"},{"key":"S2045796024000374_ref23","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199511000-00001"},{"key":"S2045796024000374_ref34","doi-asserted-by":"publisher","DOI":"10.1007\/BF03345535"},{"key":"S2045796024000374_ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011864"},{"key":"S2045796024000374_ref36","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-021-01703-1"},{"key":"S2045796024000374_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00682-6"},{"key":"S2045796024000374_ref6","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-9-356"},{"key":"S2045796024000374_ref32","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-041217-011106"},{"key":"S2045796024000374_ref17","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2020.20030305"},{"key":"S2045796024000374_ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-019-0791-8"},{"key":"S2045796024000374_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2009.06.007"},{"key":"S2045796024000374_ref31","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2018.20.1\/klrooney"},{"key":"S2045796024000374_ref13","first-page":"137","article-title":"Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019","volume":"9","year":"2023","journal-title":"The Lancet Psychiatry"},{"key":"S2045796024000374_ref5","unstructured":"Centers for disease control and prevention (2024) About stillbirth. https:\/\/www.cdc.gov\/stillbirth\/about\/index.html#:~:text=A%20stillbirth%20is%20the%20loss,the%2020th%20week%20of%20pregnancy. 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