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Subjects included 15 first-episode and 20 chronic schizophrenic patients (with the duration of illness more than 5 years), and 21 control subjects. The first-episode and chronic patients had significantly elevated error percent (<jats:italic>p<\/jats:italic> &lt; .05, effect size 1.10 and <jats:italic>p<\/jats:italic> &lt; .001, effect size 1.25), increased AS latencies (<jats:italic>p<\/jats:italic> &lt; .01, effect size 1.18 and <jats:italic>p<\/jats:italic> &lt; .001, effect size 1.69), and increased latencies variability (<jats:italic>p<\/jats:italic> &lt; .01, effect size 1.52 and <jats:italic>p<\/jats:italic> &lt; .001, effect size 1.37) compared to controls. Chronic patients had marginally significant increase of the response latency (<jats:italic>p<\/jats:italic> = .086, effect size .78) and latency variability (<jats:italic>p<\/jats:italic> &lt; .099, effect size .63) compared to first-episode ones. Results of CNV analysis revealed that chronic patients only exhibited robustly declined frontal CNV amplitude at Fz (<jats:italic>p<\/jats:italic> &lt; .05, effect size .70), F3 (<jats:italic>p<\/jats:italic> &lt; .05, effect size .88), and F4 (<jats:italic>p<\/jats:italic> &lt; .05, effect size .71) sites compared to controls. The obtained results might be related to specific changes in prefrontal cortex function over the course of schizophrenia.<\/jats:p>","DOI":"10.1017\/sjp.2017.40","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T05:30:13Z","timestamp":1508995813000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["The Study of the Antisaccade Performance and Contingent Negative Variation Characteristics in First-Episode and Chronic Schizophrenia Patients"],"prefix":"10.1017","volume":"20","author":[{"given":"Anna V.","family":"Kirenskaya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrej A.","family":"Tkachenco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir 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