{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:43:49Z","timestamp":1780731829584,"version":"3.54.1"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T00:00:00Z","timestamp":1341446400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Twin Res Hum Genet"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p><jats:italic>Aim:<\/jats:italic>To determine whether or not the change in cervical length (CL) over time is valuable in predicting spontaneous preterm delivery (SPTD) in asymptomatic twin pregnancies with a normal mid-trimester CL (&gt;25 mm).<jats:italic>Methods:<\/jats:italic>This was a prospective study including 190 consecutive asymptomatic twin gestations with a CL &gt; 25 mm at 20\u201324 weeks. The women underwent an initial CL measurement at the time of routine ultrasound examination between 20 and 24 weeks\u2019 gestation, followed 4\u20135 weeks later by a repeat CL measurement. The primary outcome measure was SPTD at &lt;32 completed weeks\u2019 gestation. Multicollinearity was a concern in the multivariable model since change in CL and follow-up CL were highly correlated.<jats:italic>Results:<\/jats:italic>The rate of SPTD at &lt;32 weeks was 4.2%. Multiple logistic regression analyses demonstrated that the change in CL and the follow-up CL were significantly associated with SPTD before 32 weeks after adjusting for baseline covariate such as in vitro fertilization. The best cut-off values for the prediction of SPTD at &lt;32 weeks\u2019 gestation were 13% for the change in CL with a sensitivity of 87.5% and a specificity of 63.2%. There was no significant difference in the area under the receiver operating characteristic curves between the change in CL and the follow-up CL.<jats:italic>Conclusions:<\/jats:italic>A greater change in CL is a good predictor of SPTD in asymptomatic twin pregnancies with a normal mid-trimester CL. However, the change in CL cannot provide data beyond the follow-up CL. In the setting of a normal mid-trimester CL, a follow-up CL measurement should be considered in asymptomatic twin pregnancies.<\/jats:p>","DOI":"10.1017\/thg.2012.27","type":"journal-article","created":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T13:07:39Z","timestamp":1341493659000},"page":"516-521","source":"Crossref","is-referenced-by-count":12,"title":["The Change in Cervical Length Over Time as a Predictor of Preterm Delivery in Asymptomatic Women With Twin Pregnancies Who Have a Normal Mid-Trimester Cervical Length"],"prefix":"10.1017","volume":"15","author":[{"given":"Kyung Joon","family":"Oh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyo Hoon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Ha","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Youn","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aeli","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Nae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2012,7,5]]},"reference":[{"key":"S1832427412000278_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3902"},{"key":"S1832427412000278_ref14","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1034\/j.1600-0412.2000.079010851.x","article-title":"Cervical length assessment in twin pregnancies using transvaginal ultrasound","volume":"79","author":"Ong","year":"2000","journal-title":"Acta Obstetricia et Gynecologia Scandinavica"},{"key":"S1832427412000278_ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1990.tb02440.x"},{"key":"S1832427412000278_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.02.064"},{"key":"S1832427412000278_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1048"},{"key":"S1832427412000278_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.06.018"},{"key":"S1832427412000278_ref4","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"S1832427412000278_ref12","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.123058"},{"key":"S1832427412000278_ref16","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2007.22.1.89"},{"key":"S1832427412000278_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7338"},{"key":"S1832427412000278_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.11.001"},{"key":"S1832427412000278_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70032-2"},{"key":"S1832427412000278_ref18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00087.x"},{"key":"S1832427412000278_ref1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.150"},{"key":"S1832427412000278_ref15","first-page":"450","article-title":"Cervical length at 23 weeks in twins in predicting spontaneous preterm delivery","volume":"94","author":"Souka","year":"1999","journal-title":"Obstetrics and Gynecology"},{"key":"S1832427412000278_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.09.004"},{"key":"S1832427412000278_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)80051-2"},{"key":"S1832427412000278_ref10","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.108896"}],"container-title":["Twin Research and Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1832427412000278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T11:48:59Z","timestamp":1714132139000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1832427412000278\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,5]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S1832427412000278"],"URL":"https:\/\/doi.org\/10.1017\/thg.2012.27","relation":{},"ISSN":["1832-4274","1839-2628"],"issn-type":[{"value":"1832-4274","type":"print"},{"value":"1839-2628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,5]]}}}