{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T14:15:01Z","timestamp":1774620901881,"version":"3.50.1"},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T00:00:00Z","timestamp":1484870400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Twin Res Hum Genet"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p>The presence of <jats:italic>situs inversus totalis<\/jats:italic> (full reversal of internal organs) in twins is briefly reviewed. Information gathered from 35-year-old monozygotic (MZ) female twin pair discordant for this condition is presented. This is followed by summaries of research on the frequency of trisomy 21 (Down syndrome) in twins, the first case of MZ twin concordance for bilateral coronoid hyperplasia, prenatal hormonal effects in mixed-sex non-human primate litters, and links between insurance mandates and twinning following in vitro fertilization. The final section of this article describes twin-related events reported in the news, namely, the first recorded birth of identical twin puppies; the 100th birthday celebration of a pair of fraternal female twins, the passing of an award-winning identical twin production designer, and the first running of the New York City Marathon by a set of quadruplets.<\/jats:p>","DOI":"10.1017\/thg.2016.101","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T06:02:14Z","timestamp":1484892134000},"page":"90-95","source":"Crossref","is-referenced-by-count":7,"title":["<i>Situs Inversus Totalis<\/i> in Twins: A Brief Review and a Life History \/ Twin Research: Twin Studies of Trisomy 21; Monozygotic Twin Concordance for Bilateral Coronoid Hyperplasia; Prenatal Hormonal Effects in Mixed-Sex Non-Human Primate Litters; Insurance Mandates and Twinning After In Vitro Fertilization \/ News Reports: First Report of Identical Twin Puppies; Twins Sisters Turn 100; Remembering an Identical Twin Production Designer; New York City Marathon Quadruplets"],"prefix":"10.1017","volume":"20","author":[{"given":"Nancy L.","family":"Segal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,1,20]]},"reference":[{"key":"S1832427416001018_ref023","unstructured":"Wilhelm A. , & Holbert J. M. (2016). Situs inversus imaging. Medscape. Retrieved from http:\/\/emedicine.medscape.com\/article\/413679-overview"},{"key":"S1832427416001018_ref001","unstructured":"Abbasi Z. (2013). Situs inversus totalis. Retrieved from http:\/\/situsinversustotalis.com"},{"key":"S1832427416001018_ref015","unstructured":"Pilon M. (2016, October 23). The New York City marathon quadruplets. The New Yorker. Retrieved from http:\/\/www.newyorker.com\/news\/sporting-scene\/the-new-york-city-marathon-quadruplets"},{"key":"S1832427416001018_ref016","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001733"},{"key":"S1832427416001018_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2005.12.003"},{"key":"S1832427416001018_ref009","unstructured":"Hogenboom M. (31 August, 2016). A dog has given birth to the first pair of identical twin puppies. BBC. Retrieved from http:\/\/www.bbc.com\/earth\/story\/20160830-first-identical-twin-dogs-discovered"},{"key":"S1832427416001018_ref018","volume-title":"Twin myth conceptions: False beliefs, fables, and facts about twins","author":"Segal"},{"key":"S1832427416001018_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/s10006-016-0578-x"},{"key":"S1832427416001018_ref013","unstructured":"Parker A. (2016, November 25). Same of the century. The Sun. Retrieved from https:\/\/www.thesun.co.uk\/news\/2260488\/these-twins-celebrate-their-100th-birthday-with-cards-from-the-queen-and-a-trip-down-the-pub\/"},{"key":"S1832427416001018_ref020","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001690"},{"key":"S1832427416001018_ref008","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-006-0144-y"},{"key":"S1832427416001018_ref021","first-page":"2,278","article-title":"Situs inversus totalis \u2014 A case report","volume":"3","author":"Supriya","year":"2013","journal-title":"IOSR International Journal of Applied Physics"},{"key":"S1832427416001018_ref003","doi-asserted-by":"publisher","DOI":"10.1089\/109264201750539754"},{"key":"S1832427416001018_ref006","doi-asserted-by":"publisher","DOI":"10.2307\/1419611"},{"key":"S1832427416001018_ref022","doi-asserted-by":"crossref","first-page":"59","DOI":"10.5923\/j.ajmms.20120203.06","article-title":"Dextrocardia with situs inversus totalis in an adult Nigerian: A case report","volume":"2","author":"Uchenna","year":"2012","journal-title":"American Journal of Medicine and Medical Sciences"},{"key":"S1832427416001018_ref005","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-013-1998-3"},{"key":"S1832427416001018_ref007","unstructured":"Grimes W. (2016, November 29). Paul Sylbert, an Oscar winner who gave movies their look, dies at 88. New York Times, p. B14."},{"key":"S1832427416001018_ref004","doi-asserted-by":"publisher","DOI":"10.1002\/ajp.22583"},{"key":"S1832427416001018_ref002","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-010-1210-2"},{"key":"S1832427416001018_ref012","unstructured":"McKinley J. (2002, March 30). Richard Sylbert, 73, designer of Oscar-winning film sets. New York Times. Retrieved from http:\/\/www.nytimes.com\/2002\/03\/30\/movies\/richard-sylbert-73-designer-of-oscar-winning-film-sets.html"},{"key":"S1832427416001018_ref011","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320340236"},{"key":"S1832427416001018_ref017","volume-title":"Entwined lives: Twins and what they tell us about human behavior","author":"Segal","year":"2000"},{"key":"S1832427416001018_ref019","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2010.140"}],"container-title":["Twin Research and Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1832427416001018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T23:48:24Z","timestamp":1555544904000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1832427416001018\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,20]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S1832427416001018"],"URL":"https:\/\/doi.org\/10.1017\/thg.2016.101","relation":{},"ISSN":["1832-4274","1839-2628"],"issn-type":[{"value":"1832-4274","type":"print"},{"value":"1839-2628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,20]]}}}