{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:55:16Z","timestamp":1769086516249,"version":"3.49.0"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"unspecified","delay-in-days":28,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Twin Res Hum Genet"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to analyze differences in birth weight and overweight\/obesity in a Shanghai twin cohort. We also wanted to study their association and explore possible risk factors for the discordance of overweight\/obesity within twins. This was an internal case\u2013control study designed for twins. The 2012 Shanghai Twin Registration System baseline survey data of a total of 3417 twin pairs were statistically analyzed using SPSS22 software. Results show that the body mass index (BMI) of the Shanghai twin population increased with age. Twins with a high birth weight had a higher BMI and a higher rate of overweight and obesity; 0- to 6-year-old twins, male twins and dizygotic (DZ) twins had higher rates of overweight\/obesity than other groups. The greater the discordant birth weight rate of twins, the more obvious the difference in BMI (<jats:italic>p<\/jats:italic> &lt; .05). There was a significant difference in overweight\/obesity between twins with a relative difference of birth weight \u226515% in DZ twins (<jats:italic>p<\/jats:italic> &lt; .05). DZ twins, male twins and 0- to 6-year-old twins were more likely to be discordant in overweight\/obese than others. The discordant birth weight within twins was not a risk factor for discordant overweight\/obesity. However, attention should be paid to childhood obesity, and appropriate interventions should be made at the appropriate time. Genetics may play an important role in the occurrence and development of overweight\/obesity. In conclusion, discordant growth and development in the uterus early in life may not lead to discordant weight development in the future.<\/jats:p>","DOI":"10.1017\/thg.2021.2","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T10:22:31Z","timestamp":1614594151000},"page":"29-36","source":"Crossref","is-referenced-by-count":3,"title":["Differences and Correlation Analysis of Birth Weight and Overweight\/Obesity in Shanghai Twin Cohort"],"prefix":"10.1017","volume":"24","author":[{"given":"Ping","family":"Liao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Ting","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-Jie","family":"Zang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nai-Si","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Jing","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can-Qing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,3,1]]},"reference":[{"key":"S1832427421000025_ref35","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq169"},{"key":"S1832427421000025_ref30","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7325.1331"},{"key":"S1832427421000025_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2015.07.006"},{"key":"S1832427421000025_ref5","doi-asserted-by":"publisher","DOI":"10.1375\/136905203322686536"},{"key":"S1832427421000025_ref26","unstructured":"National Center for Health Statistics (US). (2012). Health, United States, 2011: With Special Feature on Socioeconomic Status and Health."},{"key":"S1832427421000025_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-198809000-00002"},{"key":"S1832427421000025_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38586.411273.E0"},{"key":"S1832427421000025_ref18","first-page":"115","article-title":"Change trend of birth weight of twins in China, 1995\u20132012","volume":"36","author":"Liu","year":"2015","journal-title":"Chinese Journal of Epidemiology"},{"key":"S1832427421000025_ref21","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28868"},{"key":"S1832427421000025_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S0001566000003536"},{"key":"S1832427421000025_ref14","first-page":"97","article-title":"Body mass index reference norm for screening overweight and obesity in Chinese children and adolescents","volume":"25","year":"2004","journal-title":"Chinese Journal of Epidemiology"},{"key":"S1832427421000025_ref31","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1995.02170180083016"},{"key":"S1832427421000025_ref41","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn213"},{"key":"S1832427421000025_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyx031"},{"key":"S1832427421000025_ref8","year":"2006","journal-title":"Guidelines for the prevention and control of overweight and obesity in Chinese adults"},{"key":"S1832427421000025_ref42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2007.00440.x"},{"key":"S1832427421000025_ref43","doi-asserted-by":"publisher","DOI":"10.1007\/s10519-015-9711-0"},{"key":"S1832427421000025_ref28","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7240.967"},{"key":"S1832427421000025_ref24","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-136-12-200206180-00006"},{"key":"S1832427421000025_ref38","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-0472"},{"key":"S1832427421000025_ref19","first-page":"464","article-title":"A co-twin control study on birth weight, overweight and obesity among children younger than 18 years old in China","volume":"37","author":"Liu","year":"2016","journal-title":"Chinese Journal of Epidemiology"},{"key":"S1832427421000025_ref16","first-page":"776","article-title":"The trend analysis of overweight and obesity in Chinese students during 1985\u20132010","volume":"46","author":"Jun","year":"2012","journal-title":"Chinese Journal of Preventive Medicine"},{"key":"S1832427421000025_ref23","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801743"},{"key":"S1832427421000025_ref25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2005.00608.x"},{"key":"S1832427421000025_ref13","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802271"},{"key":"S1832427421000025_ref29","doi-asserted-by":"publisher","DOI":"10.1136\/adc.82.3.202"},{"key":"S1832427421000025_ref36","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.4951"},{"key":"S1832427421000025_ref33","first-page":"623","article-title":"The effect of high birth weight on overweight and obesity in childhood and adolescence. A cohort study in China","volume":"34","author":"Ren","year":"2013","journal-title":"Saudi Medical Journal"},{"key":"S1832427421000025_ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2012.00029"},{"key":"S1832427421000025_ref39","unstructured":"World Health Organization (WHO). (2006). WHO Child Growth Standards: Length\/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. Retrieved from https:\/\/www.who.int\/publications\/i\/item\/924154693X"},{"key":"S1832427421000025_ref3","first-page":"653","article-title":"Study on relationship between birth weight and child simple obesity","volume":"23","author":"Bingrong","year":"2007","journal-title":"Chinese Journal of Public Health"},{"key":"S1832427421000025_ref9","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.07.043497"},{"key":"S1832427421000025_ref20","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.4944"},{"key":"S1832427421000025_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2005.00615.x"},{"key":"S1832427421000025_ref17","doi-asserted-by":"publisher","DOI":"10.1017\/thg.2012.148"},{"key":"S1832427421000025_ref11","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1071"},{"key":"S1832427421000025_ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2015.11.012"},{"key":"S1832427421000025_ref32","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1242\/jeb.107151","article-title":"Twin methodology in epigenetic studies","volume":"218","author":"Qihua","year":"2015","journal-title":"Journal of Experimental Biology"},{"key":"S1832427421000025_ref7","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.127"},{"key":"S1832427421000025_ref27","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.732"},{"key":"S1832427421000025_ref37","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.111.015818"},{"key":"S1832427421000025_ref34","doi-asserted-by":"publisher","DOI":"10.1590\/S1415-790X2010000200007"},{"key":"S1832427421000025_ref2","first-page":"733","article-title":"The developmental origins of adult disease","volume":"18","author":"Barker","year":"2003","journal-title":"Journal of the American College of Nutrition"}],"container-title":["Twin Research and Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1832427421000025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T13:42:19Z","timestamp":1619444539000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1832427421000025\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S1832427421000025"],"URL":"https:\/\/doi.org\/10.1017\/thg.2021.2","relation":{},"ISSN":["1832-4274","1839-2628"],"issn-type":[{"value":"1832-4274","type":"print"},{"value":"1839-2628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2]]}}}