{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T03:32:24Z","timestamp":1767151944751,"version":"build-2238731810"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"4-5","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Twin Res Hum Genet"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Whether assisted hatching (AH) is associated with a higher incidence of monozygotic twinning (MZT) in women undergoing assisted reproductive technology remains controversial; the aim of the study was to demonstrate the relationship between AH and MZT. A total of 8900 clinical pregnancies were selected among embryo transfer cycles from January 2011 to October 2019. Women receiving day (D) 3 embryos were divided into groups A\u2013C: group A (\n                    <jats:italic>n<\/jats:italic>\n                    = 1651) and group B (\n                    <jats:italic>n<\/jats:italic>\n                    = 1045) included women aged \u226437 or \u226538 years, respectively, with zona pellucida (ZP) thinning; group C (\n                    <jats:italic>n<\/jats:italic>\n                    = 3865) included women aged \u226437 years without AH. Women aged \u226437 years who underwent blastocyst transfer and\/or blastocyst ZP breaching were included in group D (\n                    <jats:italic>n<\/jats:italic>\n                    = 2339). The incidence of MZT was compared among groups A, B and C, and between groups C and D. The incidence of MZT in group B (2.2%) was significantly higher than in group A (1.0%), especially following intracytoplasmic sperm injection (ICSI), while the incidence of MZT in group A (1.0%) was significantly lower than in group C (2.2%). The MZT rate with in\u00a0vitro fertilization was higher in group D (2.8%) than in group C (2.2%), but the MZT rate following ICSI was not significantly different between the two groups. ZP thinning of D3 embryos may increase the risk of MZT in older women (\u226538 years), but decrease it in younger women (\u226437 years). ZP breaching may be useful to reduce the incidence of MZT in ICSI-generated blastocysts.\n                  <\/jats:p>","DOI":"10.1017\/thg.2022.27","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T05:40:14Z","timestamp":1664430014000},"page":"202-205","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Assisted Hatching on Monozygotic Twinning is Related to Female Age and Insemination Method: A New Perspective"],"prefix":"10.1017","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2056-2524","authenticated-orcid":false,"given":"Chengjun","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ketong","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gensheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Shang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuefang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunjin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"S1832427422000275_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)92688-2"},{"key":"S1832427422000275_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.12.088"},{"key":"S1832427422000275_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-008-9214-5"},{"key":"S1832427422000275_ref11","doi-asserted-by":"publisher","DOI":"10.1017\/S0967199406003625"},{"key":"S1832427422000275_ref18","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1097\/01.AOG.0000143828.41271.6c","article-title":"Twin-twin transfusion syndrome: A population-based study","volume":"104","author":"Samawal","year":"2004","journal-title":"Obstetrics and Gynecology"},{"key":"S1832427422000275_ref8","article-title":"The risk of secondary sex ratio imbalance and increased monozygotic twinning after blastocyst transfer: Data from the Japan Environment and Children\u2019s Study","volume":"17","author":"Hattori","year":"2019","journal-title":"Journal of Reproductive Biology and Endocrinology"},{"key":"S1832427422000275_ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0578.2006.00145.x"},{"key":"S1832427422000275_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2014.07.001"},{"key":"S1832427422000275_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.03.039"},{"key":"S1832427422000275_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr012"},{"key":"S1832427422000275_ref19","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200211000-00011"},{"key":"S1832427422000275_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.06.013"},{"key":"S1832427422000275_ref2","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.1093\/humrep\/dei142","article-title":"Consequences of vanishing twins in IVF\/ICSI pregnancies","volume":"20","author":"Anja","year":"2005","journal-title":"Human Reproduction"},{"key":"S1832427422000275_ref5","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-11-21"},{"key":"S1832427422000275_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.11.034"},{"key":"S1832427422000275_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2018.10.025"},{"key":"S1832427422000275_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)00557-4"},{"key":"S1832427422000275_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-017-2372-x"},{"key":"S1832427422000275_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmy006"},{"key":"S1832427422000275_ref6","first-page":"10","article-title":"Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins","volume":"6","author":"Christophersen","year":"2013","journal-title":"Circulation: Arrhythmia and Electrophysiology"},{"key":"S1832427422000275_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-018-1118-4"},{"key":"S1832427422000275_ref3","doi-asserted-by":"publisher","DOI":"10.1530\/REP-08-0206"}],"updated-by":[{"DOI":"10.1017\/thg.2022.37","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000}}],"container-title":["Twin Research and Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1832427422000275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T04:05:55Z","timestamp":1669608355000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1832427422000275\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,29]]},"references-count":22,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S1832427422000275"],"URL":"https:\/\/doi.org\/10.1017\/thg.2022.27","relation":{},"ISSN":["1832-4274","1839-2628"],"issn-type":[{"value":"1832-4274","type":"print"},{"value":"1839-2628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,29]]}}}