{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:00:55Z","timestamp":1790758855320,"version":"4.1.0"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Twin Res Hum Genet"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Growth disorders are common in in vitro fertilization (IVF)-conceived twins, but risk factors specific to dichorionic-diamniotic twins remain incompletely characterized. This study aimed to assess these risk factors. Data from in vitro fertilization pregnancies (December 2020 \u2013 November 2024) were retrospectively analyzed. Small for gestational age was defined as estimated fetal weight below the 10th percentile. Intertwin discordance greater than 15% was considered significant. Change in uterine artery pulsatility index was calculated by subtracting first-trimester from second-trimester values. Of 169 dichorionic-diamniotic twin pregnancies, 30 (17.8%) were from fresh embryo transfer and 139 (82.2%) from frozen embryo transfer. Mean uterine artery pulsatility index was higher in the fresh group in both trimesters (first: 1.72 vs. 1.30; second: 0.91 vs. 0.78; both\n                    <jats:italic>p<\/jats:italic>\n                    = .001). Small for gestational age incidence was similar between groups (56.7% vs. 50.3%,\n                    <jats:italic>p<\/jats:italic>\n                    = .441), as was significant discordance (36.6% vs. 25.9%,\n                    <jats:italic>p<\/jats:italic>\n                    = .081). Logistic regression identified advanced maternal age (odds ratio: 1.07, 95% CI [1.00, 1.14];\n                    <jats:italic>p<\/jats:italic>\n                    = .024), higher first-trimester uterine artery pulsatility index (\n                    <jats:italic>OR<\/jats:italic>\n                    2.19, 95% CI [1.27, 3.76];\n                    <jats:italic>p<\/jats:italic>\n                    = .002), and preeclampsia (\n                    <jats:italic>OR<\/jats:italic>\n                    3.74, 95% CI [1.19, 11.67];\n                    <jats:italic>p<\/jats:italic>\n                    = .023) as predictors of small for gestational age. For significant discordance, predictors were second-trimester intertwin estimated fetal weight difference (\n                    <jats:italic>OR<\/jats:italic>\n                    1.03, 95% CI [1.01, 1.04];\n                    <jats:italic>p<\/jats:italic>\n                    = .001) and change in uterine artery pulsatility index (odds ratio: 2.51, 95% CI [1.01, 6.22];\n                    <jats:italic>p<\/jats:italic>\n                    = .047). Uterine artery pulsatility index and second-trimester biometric differences independently predict small for gestational age and intertwin discordance in IVF-conceived dichorionic-diamniotic twin pregnancies.\n                  <\/jats:p>","DOI":"10.1017\/thg.2026.10093","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:25:32Z","timestamp":1790756732000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Fetal Growth Disorders in Dichorionic Diamniotic IVF Twin Pregnancies: A Retrospective Longitudinal Cohort Study"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7621-7503","authenticated-orcid":false,"given":"Semir","family":"K\u00f6se","sequence":"first","affiliation":[{"name":"\u0130renbe Obstetric Gynecology and IVF Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7a\u011flasu","family":"Sancaktar","sequence":"additional","affiliation":[{"name":"\u0130zmir Atat\u00fcrk Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alper","family":"Biler","sequence":"additional","affiliation":[{"name":"\u0130renbe Obstetric Gynecology and IVF Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00dcmit","family":"\u0130nceboz","sequence":"additional","affiliation":[{"name":"\u0130renbe Obstetric Gynecology and IVF Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"S1832427426100930_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/uog.23698"},{"key":"S1832427426100930_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/uog.29166"},{"key":"S1832427426100930_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deae010"},{"key":"S1832427426100930_ref30","article-title":"Fresh versus frozen embryo transfers in assisted reproduction","author":"Zaat","year":"2021","journal-title":"Cochrane Database of Systematic 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women","author":"\u010cebron","year":"2025","journal-title":"Journal of Perinatal 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