{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:19:03Z","timestamp":1790857143582,"version":"4.1.0"},"reference-count":53,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"unspecified","delay-in-days":161,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"publisher","award":["F-113947"],"award-info":[{"award-number":["F-113947"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Wearable Technol."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Upper-limb occupational exoskeletons reduce injuries during overhead work. Previous studies focused on muscle activation with and without exoskeletons, but their impact on shoulder fatigue remains unclear. Additionally, no studies have explored how exoskeleton support levels affect fatigue. This study investigates the effects of assistive profiles on muscular and cardiovascular fatigue. Electromyographic (EMG) and electrocardiographic signals were collected to compute EMG median frequency (MDF), heart rate (HR), and heart rate variability (HRV). Fatigue was assessed using three MDF and HR metrics: relative change (<jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline1.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{MDF}}_{\\Delta  } $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>,<jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline2.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{HR}}_{\\Delta  } $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>), slope (<jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline3.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{MDF}}_{\\mathrm{slope}} $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>,<jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline4.png\"\/>\n\t\t<jats:tex-math>$ \\mathrm{H}{\\mathrm{R}}_{\\mathrm{slope}} $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>), and intercept (<jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline5.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{MDF}}_{\\mathrm{intercept}} $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>,<jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline6.png\"\/>\n\t\t<jats:tex-math>$ \\mathrm{H}{\\mathrm{R}}_{\\mathrm{intercept}} $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>) of the linear regression. Results showed  <jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline7.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{MDF}}_{\\Delta  } $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula>decreased 64% (<jats:italic>p<\/jats:italic> = 0.0020) with higher assistance compared to no exoskeleton; <jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline8.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{HR}}_{\\Delta  } $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula> decreased 40% (<jats:italic>p<\/jats:italic> &lt; 0.0273) with lower assistance, <jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline9.png\"\/>\n\t\t<jats:tex-math>$ {\\mathrm{MDF}}_{\\mathrm{slope}} $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula> decreased up to 67% (<jats:italic>p<\/jats:italic> = 0.0039) and <jats:inline-formula>\n\t      <jats:alternatives>\n\t\t<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mime-subtype=\"png\" xlink:href=\"S263171762510008X_inline10.png\"\/>\n\t\t<jats:tex-math>$ \\mathrm{H}{\\mathrm{R}}_{\\mathrm{slope}} $<\/jats:tex-math>\n\t      <\/jats:alternatives>\n\t    <\/jats:inline-formula> by 43% (<jats:italic>p<\/jats:italic> &lt; 0.0098) with higher and medium assistance. HRV metrics included root mean square of successive differences (RMSSD) and low-frequency to high-frequency power ratio (LF\/HF). RMSSD indicated parasympathetic dominance, while rising LF\/HF ratio suggested physiological strain. Findings support occupational exoskeletons as ergonomic tools for reducing fatigue.<\/jats:p>","DOI":"10.1017\/wtc.2025.10008","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T06:02:22Z","timestamp":1749621742000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of fatigue progression during overhead tasks and the effects of exoskeleton assistance"],"prefix":"10.1017","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3715-9792","authenticated-orcid":false,"given":"Seemab","family":"Zakir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4899-9346","authenticated-orcid":false,"given":"Lorenzo","family":"Grazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Giovacchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Vitiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"Trigili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9833-4401","authenticated-orcid":false,"given":"Simona","family":"Crea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,6,11]]},"reference":[{"key":"S263171762510008X_r44","doi-asserted-by":"publisher","DOI":"10.1080\/24725838.2019.1638331"},{"key":"S263171762510008X_r12","doi-asserted-by":"publisher","DOI":"10.1080\/00140139.2015.1081988"},{"key":"S263171762510008X_r6","doi-asserted-by":"publisher","DOI":"10.52082\/jssm.2023.806"},{"key":"S263171762510008X_r15","doi-asserted-by":"publisher","DOI":"10.1179\/1743288X11Y.0000000032"},{"key":"S263171762510008X_r28","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-72531-4"},{"key":"S263171762510008X_r43","doi-asserted-by":"publisher","DOI":"10.1016\/j.promfg.2017.07.252"},{"key":"S263171762510008X_r30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2007.08.006"},{"key":"S263171762510008X_r23","doi-asserted-by":"publisher","DOI":"10.1109\/TNSRE.2020.3014408"},{"key":"S263171762510008X_r32","volume-title":"Occupational exoskeletons: Wearable robotic devices to prevent work-related musculoskeletal disorders in the workplace of the future","author":"Monica","year":"2020"},{"key":"S263171762510008X_r1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autcon.2017.07.007"},{"key":"S263171762510008X_r14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ergon.2023.103476"},{"key":"S263171762510008X_r5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2008.04.014"},{"key":"S263171762510008X_r41","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2017.00258"},{"key":"S263171762510008X_r8","doi-asserted-by":"publisher","DOI":"10.1016\/S0263-2241(99)00059-7"},{"key":"S263171762510008X_r16","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2010.0094"},{"key":"S263171762510008X_r46","doi-asserted-by":"publisher","DOI":"10.1016\/j.autcon.2020.103079"},{"key":"S263171762510008X_r11","volume-title":"Work\u2013related musculoskeletal disorders \u2013 Prevalence, costs and demographics in the EU","author":"De Kok","year":"2019"},{"key":"S263171762510008X_r47","doi-asserted-by":"publisher","DOI":"10.1109\/MeMeA49120.2020.9137299"},{"key":"S263171762510008X_r50","doi-asserted-by":"publisher","DOI":"10.3390\/app14209166"},{"key":"S263171762510008X_r29","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2007.02.015"},{"key":"S263171762510008X_r53","unstructured":"O\u2019Neill, C. and Panuwatwanich, K. 2013. 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