{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:06:32Z","timestamp":1762160792790},"reference-count":20,"publisher":"Hindawi Limited","issue":"1","license":[{"start":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T00:00:00Z","timestamp":1239667200000},"content-version":"unspecified","delay-in-days":15597,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Res."],"published-print":{"date-parts":[[1966,8]]},"abstract":"<jats:p>1. In the transduction<jats:italic>pro<\/jats:italic>-401 (\u00d7) + some of the transductants are surrounded by several hundred small wild-type satellite colonies; these transductants spontaneously release phage which transduces<jats:italic>pro<\/jats:italic>-401 to wild-type at high frequency (HFT phage).<\/jats:p><jats:p>2. When the HFT phage is used to infect<jats:italic>pro<\/jats:italic>-401 at very low multiplicities of infection, most of the transductants are defective lysogens and segregate proline-requiring phage-sensitive derivatives; these transductants are apparently heterogenotes. At higher multiplicities of infection, or with lysogenic recipients, a higher proportion of satellited transductants is found.<\/jats:p><jats:p>3. The HFT phage preparations transduce only the proline region of the donor genome.<\/jats:p><jats:p>4. The existence is inferred of a defective P22 particle specifically incorporating the proline region of the<jats:italic>Salmonella<\/jats:italic>chromosome; these defective particles can establish themselves as prophage and confer immunity upon the infected cell, but are unable to replicate unless a normal prophage is also present. Satellited transductants are lysogenic both for a normal and defective (proline region carrying) phage, and so on lysis release transducing phage.<\/jats:p><jats:p>5. This system is compared with the \u03bb<jats:italic>dg-gal<\/jats:italic>and P1-<jats:italic>dl-lac<\/jats:italic>systems in<jats:italic>E. coli.<\/jats:italic><\/jats:p>","DOI":"10.1017\/s0016672300009927","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T07:57:42Z","timestamp":1253174262000},"page":"73-82","source":"Crossref","is-referenced-by-count":19,"title":["Restricted trandsuction by bacteriophage P22 in<i>Salmonella typhimurium<\/i>"],"prefix":"10.1155","volume":"8","author":[{"given":"P. F.","family":"Smith-Keary","sequence":"first","affiliation":[]}],"member":"98","published-online":{"date-parts":[[2009,4,14]]},"reference":[{"key":"S0016672300009927_ref014","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1960.5"},{"key":"S0016672300009927_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(60)90080-5"},{"key":"S0016672300009927_ref007","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(61)90362-2"},{"key":"S0016672300009927_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(59)80021-8"},{"key":"S0016672300009927_ref019","first-page":"43","volume-title":"Perspectives in Virology","author":"Zinder","year":"1959"},{"key":"S0016672300009927_ref004","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1958.023.01.011"},{"key":"S0016672300009927_ref015","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300001221"},{"key":"S0016672300009927_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(65)90166-2"},{"key":"S0016672300009927_ref016","first-page":"523","article-title":"\u00dcber einen defekt des transduzierenden Salmonella-phagen P22 \u00fcbert ragenen materials","volume":"14b","author":"Starlinger","year":"1958","journal-title":"Z. Naturf."},{"key":"S0016672300009927_ref020","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1128\/JB.64.5.679-699.1952","article-title":"Genetic exchange in Salmonella","volume":"64","author":"Zinder","year":"1952","journal-title":"J. Bact."},{"key":"S0016672300009927_ref001","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.44.6.590"},{"key":"S0016672300009927_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(57)90070-3"},{"key":"S0016672300009927_ref002","first-page":"659","article-title":"La d\u00e9fectuosit\u00e9 du phage lambda transducteur","volume":"20","author":"Arber","year":"1957","journal-title":"Schweiz. Z. allg. Path. Bakt."},{"key":"S0016672300009927_ref006","doi-asserted-by":"publisher","DOI":"10.1038\/2041112a0"},{"key":"S0016672300009927_ref008","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1951.016.01.030"},{"key":"S0016672300009927_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(55)90016-7"},{"key":"S0016672300009927_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(60)90161-6"},{"key":"S0016672300009927_ref011","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/genetics\/41.1.142","article-title":"Transduction in Escherichia coli K-12","volume":"41","author":"Morse","year":"1956","journal-title":"Genetics"},{"key":"S0016672300009927_ref012","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1093\/genetics\/41.5.758","article-title":"Transduction heterogenotes in Escherichia coli","volume":"41","author":"Morse","year":"1956","journal-title":"Genetics"},{"key":"S0016672300009927_ref017","doi-asserted-by":"publisher","DOI":"10.1038\/2011298a0"}],"container-title":["Genetical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0016672300009927","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T22:54:08Z","timestamp":1633906448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0016672300009927\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,8]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1966,8]]}},"alternative-id":["S0016672300009927"],"URL":"https:\/\/doi.org\/10.1017\/s0016672300009927","relation":{},"ISSN":["0016-6723","1469-5073"],"issn-type":[{"value":"0016-6723","type":"print"},{"value":"1469-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[1966,8]]}}}