{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:58:39Z","timestamp":1761580719025},"reference-count":10,"publisher":"Hindawi Limited","issue":"2","license":[{"start":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T00:00:00Z","timestamp":1239667200000},"content-version":"unspecified","delay-in-days":12432,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Res."],"published-print":{"date-parts":[[1975,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The charge state model of Ohta &amp; Kimura (1973) for the number of electrophoretically detectable alleles in a finite population, is extended to include mutations of both one and two charge changes. The effective number of alleles (<jats:italic>n<jats:sub>e<\/jats:sub><\/jats:italic>) is increased only slightly by this extension. Electrophoretic profiles of neutral variants are shown on average to be leptokurtic and have their odd central moments equal to zero. The expected frequency distribution of pairs of gametes which differ by 1,2,3,\u2026 charge units can be obtained as the sum of the appropriate terms from two geometric series.<\/jats:p>","DOI":"10.1017\/s0016672300015536","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T07:48:42Z","timestamp":1253173722000},"page":"137-143","source":"Crossref","is-referenced-by-count":15,"title":["Profiles of electrophoretic alleles in natural populations"],"prefix":"10.1155","volume":"25","author":[{"given":"A. H. D.","family":"Brown","sequence":"first","affiliation":[]},{"given":"D. R.","family":"Marshall","sequence":"additional","affiliation":[]},{"given":"L.","family":"Albrecht","sequence":"additional","affiliation":[]}],"member":"98","published-online":{"date-parts":[[2009,4,14]]},"reference":[{"key":"S0016672300015536_ref003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.1955.tb01551.x"},{"key":"S0016672300015536_ref007","volume-title":"Population Genetics","author":"Li","year":"1955"},{"key":"S0016672300015536_ref002","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.12.3928"},{"key":"S0016672300015536_ref004","doi-asserted-by":"publisher","DOI":"10.1038\/229467a0"},{"key":"S0016672300015536_ref005","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1093\/genetics\/76.3.607","article-title":"Isoallele frequencies in very large populations","volume":"76","author":"King","year":"1974","journal-title":"Genetics"},{"key":"S0016672300015536_ref006","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1093\/genetics\/54.2.595","article-title":"A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura","volume":"54","author":"Lewontin","year":"1966","journal-title":"Genetics"},{"key":"S0016672300015536_ref008","article-title":"The charge-state model of protein polymorphism in natural populations","author":"Marshall","year":"1974","journal-title":"Journal of Molecular Evolution"},{"key":"S0016672300015536_ref009","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300012994"},{"key":"S0016672300015536_ref001","first-page":"211","article-title":"Darwinian versus non-Darwinian evolution in natural populations of Drosophila","volume":"v","author":"Ayala","year":"1972","journal-title":"Proceedings 6th Berkeley Symposium Mathematical Statistics and Probability"},{"key":"S0016672300015536_ref010","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/genetics\/76.3.615","article-title":"Simulation studies on electrophoretically detectable genetic variability in a finite population","volume":"76","author":"Ohta","year":"1974","journal-title":"Genetics"}],"container-title":["Genetical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0016672300015536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T22:50:48Z","timestamp":1633906248000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0016672300015536\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1975,4]]}},"alternative-id":["S0016672300015536"],"URL":"https:\/\/doi.org\/10.1017\/s0016672300015536","relation":{},"ISSN":["0016-6723","1469-5073"],"issn-type":[{"value":"0016-6723","type":"print"},{"value":"1469-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,4]]}}}